Results 231 to 240 of about 46,069 (286)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Development and validation of a Novel 3D-printed mold-based silicone model for laparoscopic duodenal stump reinforcement suture simulation training. [PDF]

BMC Med Educ
Wang Q, Wang K, Wang Z, Zhu G.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Functional and Genomic Characterization of <i>Serratia quinivorans</i> NFX21 and <i>Pseudomonas thivervalensis</i> NFX104, Novel Biocontrol Agents Against <i>Botrytis cinerea</i>. [PDF]

Plants (Basel)
Tedesco S, Silva FT, Pimenta M, Bustos Gaspar F, Nunes da Silva M, Barreto Crespo MT, Nascimento FX.   +6 more
europepmc   +1 more source

Engineering the Future of Heart Failure Therapeutics: Integrating 3D Printing, Silicone Molding, and Translational Development for Implantable Cardiac Devices. [PDF]

Bioengineering (Basel)
Eagle C, Desai A, Franklin M, Pooley R, Johnson E, Robinson S, Lopez M, Goswami R.   +7 more
europepmc   +1 more source

A composition-matching algorithm, MatchIDR, identifies prion-like domains that localize to stress granules. [PDF]

Protein Sci
Cascarina SM, Paul KR, Ford LL, Ross ED.
europepmc   +1 more source

Analysis of the Fiber Residues Unearthed from the Dabuzi Han Tomb in Xi'an, Shaanxi. [PDF]

Materials (Basel)
Ma Z, Zhu Y, Shao J, Hou X, Cui M, Zhang B, Li J, Xia Q.   +7 more
europepmc   +1 more source

ZDAM: a new deep learning model for bean leaf disease diagnosis. [PDF]

Front Plant Sci
Liu J, Yu K, Song H, Ma J, Bijani M, Wu L, Xu L, Ahmad MN, Xu P, Zhao J.   +9 more
europepmc   +1 more source

A novel method for the creation of a patient-specific realistic model of hypertrophic cardiomyopathy for surgical myectomy simulation. [PDF]

3D Print Med
García-Rodríguez S, Komatsu T, Guenther T, Thiel A, Bolling BW, Hermsen J.   +5 more
europepmc   +1 more source

Studies on the green and blue molds of Satsuma orange (5)

Japanese Journal of Phytopathology, 1963
openaire   +1 more source