Results 71 to 80 of about 45,745 (286)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Metal additive manufacturing of conformal cooling channels for improving the quality of metal injection–molded products

open access: yesAdvances in Mechanical Engineering
The primary advantage of metal injection molding (MIM) is that it can be used to mass-produce complex metal products; however, it requires a few secondary processes.
Chen-Yuan Chung, Chuan-Jen Liu
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Calculating Methods on Remained Measure of Repairing Mold in Green Product Design

open access: yes, 2010
This article primarily analyzes the shortcoming in the current formula of plastic and rubber mold shaped dimensions in practical, and fully considered the influence of plastic and rubber contracting fluctuation ratio on the accuracy of the plastic and ...
Jun An Liu   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

RANCANG BANGUN CETAKAN PEMANEN (PERMANENT MOLD) UNTUK PEMBUATAN PULLEY ALUMINIUM

open access: yes, 2010
Many efforts have been done to increase efficiencies and margin (without ignoring the quality) in casting industry. Most of the producer of non-ferrous pulleys in South Sumatra region are handled by small and medium scale industries using simple ...
Firdaus, Firdaus
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effects of chills on the solidification pattern of an axial steel cast impeller

open access: yesMetalurgija, 2015
This paper presents three-dimensional simulation of transient conduction heat transfer within an axial impeller (AISI 1016), two different sizes of chills (AISI 1016), core (green sand) and mold (green sand) by using Ansys CFX. Specific heat, density and
M. Copur, A. Turan, M. N. Eruslu
doaj  

Properties of fiber reinforced plaster molds for investment casting

open access: yesChina Foundry, 2020
In order to improve the performance of plaster molds for investment casting, a diverse content of glass fiber and polypropylene (PP) fiber was incorporated into the slurry for the preparation of a fiber-reinforced mold.
Jie Ren, Xiang Chen, Yan-xiang Li
doaj   +1 more source

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