Results 71 to 80 of about 216,759 (311)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Green Awareness and Purchase Intention for Organic Products

IOP Conference Series: Materials Science and Engineering, 2018
Organic vegetables are a healthy product that is consumed and it is friendly for environment, because it does not use pesticide material. But, customer's awareness in Indonesia selects organic vegetables is still low. Those cases are happened because customer's knowledge for organic product is still low.
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

ANALYSIS OF THE INFLUENCE OF CONSUMER PURCHASE INTENTIONS ON GREEN PRODUCT PURCHASE

Jurnal Ekonomi Trisakti, 2023
Dalam beberapa waktu terakhir, terjadi peningkatan jumlah produk ramah lingkungan yang beredar di Indonesia. Perusahaan-perusahaan yang menyediakan produk semacam itu melihat adanya peluang untuk memperoleh pangsa pasar di Indonesia. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh niat pembelian konsumen terhadap produk ramah lingkungan ...
Yoga Ferdiansyah, Luki Adiati Pratomo
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Framing descriptive norms as self-benefit versus environmental benefit : self-construal’s moderating impact in promoting smart energy devices [PDF]

, 2019
Recently, awareness has been raised concerning the importance of sustainable energy use. Nevertheless, many obstacles must be overcome to change individuals’ energy consumption habits.
Cauberghe, Veroline, Hudders, Liselot, Mingolla, Carla   +2 more
core   +1 more source

Efektivitas Green Advertising terhadap Purchase Intention pada Green Cosmetic Product

Flourishing Journal
Today, the need for skin care and make-up is a concern for women. Therefore, marketers in the cosmetics industry are using different ways to attract buyers, one of which is the technique of green advertising. This study was conducted to determine whether green advertising influences purchase intention for Love Beauty and Planet products.
null Cindyviera Zuriel Questania, null Khoyimatus Sa’adha, null Shuhaima, null Reval Furqon Nugraha, null Yaumul Rahmi   +4 more
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Do Green Lifestyle Consumers Appreciate Low Involvement Green Products? [PDF]

, 2011
Green products have become popular and have been targeted toward consumers who lead green lifestyles. Still, some green products are assumed to be more appealing to this group than others, sometimes based on level of involvement.
Arling, Priscilla, Florenthal, Bela
core   +1 more source

The Role of Green Product Trust in Mediating the Influence of Eco-Branding and Brand Uniqueness on Green Purchase Intention in KALIMBO Bag Products [PDF]

This study aims to determine the role of green product trust in mediating the influence of eco-branding and brand uniqueness on green purchase intention. This study uses a quantitative approach with 150 respondents.
Erliani, Aida, Rinuastuti, Baiq Handayani   +1 more
core   +2 more sources