Results 81 to 90 of about 1,857,789 (295)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A New Phytochemical Screening Programme used for Crops grown with Organic and Conventional Methods [PDF]

, 2002
A broad screening programme, covering the most general phytochemical groups of compounds, was developed on the basis of Thin Layer Chromatography (TLC).
Brandt, Kirsten, Christensen, Trine F., Diedrichsen, Brigitte, Kristensen, Charlotte V., Ravn, Dr. Helle Weber   +4 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Aerogels and cryogels as green sorbents for organic contaminant extraction and chromatographic analysis

Sustainable Chemistry for the Environment
In recent years, there has been increasing interest in developing more environmentally friendly analytical methods. In this context, microextraction techniques have gained wider application, and novel materials are being researched as potential ...
Ilektra C. Feida, Vasileios D. Alampanos, Justyna Płotka-Wasylka, Dimitra A. Lambropoulou   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Natural deep eutectic solvents and natural solid biosorbents in microextraction techniques of organic compounds based on chromatographic techniques: A critical review

Advances in Sample Preparation
Analytical chemistry has increasingly focused on the environmental impact of its methods, with significant attention given to green principles in sample preparation. Techniques like Solid-Phase Microextraction (SPME), Micro-Solid-Phase Extraction (µ-SPE),
Eduardo Carasek, Lucas Morés, Natan da Cunha, Guilherme Leal Branco, Adriana Neves Dias   +4 more
doaj   +1 more source

A New Calibration Methodology for Quantitative Elemental Analysis of Zeolite Compounds through WD-XRF [PDF]

Iranian Journal of Chemistry & Chemical Engineering
Considering the growing need for rapid and accurate analysis of zeolites, X-Ray Fluorescence (XRF) spectrometry is a suitable technique for fast analysis without the need for extensive sample preparation.
Azam Samiei, Seyyed Hamid Ahmadi, Mahta Badienezhad, Hamed Khani, Vahid Ameri, Azam Khani   +5 more
doaj   +1 more source

Glycolaldehyde in Perseus young solar analogs [PDF]

, 2017
Aims: In this paper we focus on the occurrence of glycolaldehyde (HCOCH2OH) in young solar analogs by performing the first homogeneous and unbiased study of this molecule in the Class 0 protostars of the nearby Perseus star forming region.
Anderl, S., Andre', Ph., Belloche, A., Codella, C., De Simone, M., Maret, S., Maury, A. J., Podio, L., Testi, L.   +8 more
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sexual Hormones Determination in Biofluids by In-Vial Polycaprolactone Thin-Film Microextraction Coupled with HPLC-MS/MS

Molecules
The in-vial microextraction technique is emerging as an alternative sample treatment, as it integrates sorbent preparation, adsorption, and desorption of analytes in a single device before instrumental analysis.
Francesca Merlo, Silvia Anselmi, Andrea Speltini, Clàudia Fontàs, Enriqueta Anticó, Antonella Profumo   +5 more
doaj   +1 more source