Results 31 to 40 of about 1,880,201 (344)

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

bioRxiv, 2018
One Sentence Summary Recurrent tonsillitis is a multifactorial disease associated with an aberrant tonsillar germinal center response to Group A Streptococcus.
J. Dan, C. Havenar-Daughton, Kayla Kendric, Rita Al-Kolla, Kirti Kaushik, S. L. Rosales, Ericka Anderson, Christopher N. LaRock, P. Vijayanand, G. Seumois, D. Layfield, R. Cutress, C. Ottensmeier, C. L. Lindestam Arlehamn, A. Sette, V. Nizet, M. Bothwell, M. Brigger, S. Crotty   +18 more
semanticscholar   +1 more source

Evaluation of a Streptococcal Pharyngitis Score in Southern Taiwan

Pediatrics and Neonatology, 2012
Group A streptococcus (GAS) pharyngitis can cause serious complications such as rheumatic heart disease. The McIsaac sore throat score is a clinical prediction score used to improve the detection rate of GAS pharyngitis.
Ching-Tang Shih, Ching-Chiang Lin, Chung-Ching Lu   +2 more
doaj   +1 more source

The effect of hydrophobicity of group a beta-hemolytic streptococcus in the process of adherence and biofilm production [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Bacterial cell hydrophobicity and adherence to a substrate are one of the most important factors in biofilm formation. Group A streptococcus is an unstable and low biofilm productor.
Šmitran Aleksandra, Marković Tatjana, Ranin Lazar   +2 more
doaj   +1 more source

Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial

PLoS ONE, 2018
Background Group A streptococcus (GAS) is a serious human pathogen that affects people of different ages and socio-economic levels. Although vaccination is potentially one of the most effective methods to control GAS infection and its sequelae, few ...
S. Sekuloski, M. Batzloff, P. Griffin, W. Parsonage, S. Elliott, J. Hartas, P. O’Rourke, L. Marquart, Manisha Pandey, F. Rubin, J. Carapetis, J. McCarthy, M. Good   +12 more
semanticscholar   +1 more source

Group A Streptococcus in the Gynecologic Patient

Infectious Diseases in Obstetrics and Gynecology, 1997
Over the past few decades, physicians have been reminded of the potential for serious complications arising from group A streptococcal (GAS) infections. These infections continue to pose a serious threat, primarily because the pathophysiology of these infections is complex.
P. Garvey, William J. Ledger
openaire   +3 more sources

Group A streptococcal primary peritonitis in an otherwise healthy adolescent female

Journal of Pediatric Surgery Case Reports, 2021
Group A streptococcal (GAS) primary peritonitis is a rare clinical entity, particularly in the pediatric population. Traditionally patients with primary peritonitis, particularly those with underlying medical conditions such as nephrotic syndrome and ...
Torbjorg Holtestaul, M.D., Allison Langs-Barlow, M.D., Meade Barlow, M.D.   +2 more
doaj  

Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda

BMC Infectious Diseases, 2017
Background Beta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of transmission. The aim of this study
Irene Nayiga, Emmy Okello, Peter Lwabi, Grace Ndeezi   +3 more
doaj   +1 more source

The fall and rise of Group A Streptococcus diseases

Epidemiology and Infection, 2018
Streptococcus pyogenes (or Group A Streptococcus, GAS) is a Gram-positive human pathogen responsible for a diverse array of superficial, invasive and immune-related diseases. GAS infections have historically been diseases of poverty and overcrowding, and
T. C. Barnett, A. Bowen, J. Carapetis
semanticscholar   +1 more source

Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against Streptococcus pyogenes

mSphere, 2018
The clinical development of group A streptococcal (GAS) vaccines will require the implementation of a standardized, high-throughput assay to measure the activity of functional opsonic antibodies in vaccine recipients. In the present study, we adapted and
Sanaz Salehi, Claudia M. Hohn, Thomas A. Penfound, James B. Dale   +3 more
doaj   +1 more source

Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations

Current Treatment Options in Cardiovascular Medicine, 2017
Opinion statementEarly recognition of group A streptococcal pharyngitis and appropriate management with benzathine penicillin using local clinical prediction rules together with validated rapi-strep testing when available should be incorporated in ...
L. Zühlke, A. Beaton, M. Engel, C. Hugo-Hamman, G. Karthikeyan, J. Katzenellenbogen, N. Ntusi, A. Ralph, A. Saxena, P. Smeesters, D. Watkins, P. Zilla, J. Carapetis   +12 more
semanticscholar   +1 more source