Results 51 to 60 of about 671,076 (285)
Topological analysis of number theory and its applications in quantum cryptography [PDF]
مجلة جامعة الانبار للعلوم الصرفةThis study investigates the application of algebraic topology, in particular homology theory and persistent homology. It includes the analysis of elliptic curves and their use in cryptographic systems and cybersecurity.
Noor Kadhim, Ruaa Abd, Saja AL-Khafaji
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Alteration in the Local and Global Functional Connectivity of Resting State Networks in Parkinson’s Disease [PDF]
Journal of Movement Disorders, 2018 Objective Parkinson’s disease (PD) is a neurodegenerative disorder that mainly leads to the impairment of patients’ motor function, as well as of cognition, as it progresses.
Maryam Ghahremani +5 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
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The homology groups of the Cartesian product $\Omega_{n_1}(m_1)\times \Omega_{n_2}(m_2)$
Researches in MathematicsThe paper continues the investigation of the spaces of complex-valued perfect splines $\Omega_n(m)$. These spaces were introduced as generalization of the spaces $\Omega_n$, the topology of which has been studied by V.I. Ruban, V.A. Koshcheev, A.M. Pasko.
A.M. Pasko
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Homology Groups of Cubical Sets [PDF]
Applied Categorical Structures, 2018 25 ...
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
cDNA cloning and molecular modeling of procerain B, a novel cysteine endopeptidase isolated from Calotropis procera. [PDF]
PLoS ONE, 2013 Procerain B, a novel cysteine protease (endopeptidase) isolated from Calotropis procera belongs to Asclepiadaceae family. Purification of the enzyme, biochemical characterization and potential applications are already published by our group.
Abhay Narayan Singh +2 more
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Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The topology of restricted partition posets [PDF]
Discrete Mathematics & Theoretical Computer Science, 2011 For each composition $\vec{c}$ we show that the order complex of the poset of pointed set partitions $Π ^• _{\vec{c}}$ is a wedge of $β\vec{c}$ spheres of the same dimensions, where $β\vec{c}$ is the number of permutations with descent composition ^$\vec{
Richard Ehrenborg, JiYoon Jung
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