Results 111 to 120 of about 23,005,860 (400)
LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling [PDF]
, 2018 Hua Liu +4 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Scaling of fault damage zones with displacement and the implications for fault growth processes [PDF]
, 2011 D. R. Faulkner +3 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
mTOR Signaling in Growth, Metabolism, and Disease
Cell, 2017 R. A. Saxton, D. Sabatini
semanticscholar +2 more sources
Scientific ReportsRecent decades have seen declining total fertility rates (TFR) globally, alongside increased use of assisted reproductive technology (ART). However, TFR includes ART births and excludes induced abortions, complicating assessments of population fecundity.
Rune Lindahl-Jacobsen +6 more
doaj +1 more source
Directing the Architecture of Cuprous Oxide Crystals during Electrochemical Growth [PDF]
, 2005 Matthew Siegfried, Kyoung‐Shin Choi
openalex +1 more source
Who do High-growth Firms Employ, and Who do they Hire? [PDF]
The purpose of this paper is to study who high- growth firms (HGFs) hire using a matched employer-employee dataset for all knowledge intensive industries in Sweden, where high growth is measured over the period 1999-2002.
Coad, Alex +3 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
IEEE AccessNon-destructive testing (NDT) is a highly regarded area on the medical, space and defense sectors but, also on heavy equipment susceptible to corrosion and hidden structural defects.
Vlad Marsic +4 more
doaj +1 more source