Results 91 to 100 of about 10,322,817 (363)

Abnormal mandibular growth and the condylar cartilage [PDF]

, 2017
Deviations in the growth of the mandibular condyle can affect both the functional occlusion and the aesthetic appearance of the face. The reasons for these growth deviations are numerous and often entail complex sequences of malfunction at the cellular ...
Luder, Hans. U., Müller, Lukas, Peltomäki, Timo, Pirttiniemi, Pertti   +3 more
core  

Genetic landscape of autism spectrum disorder in Vietnamese children [PDF]

, 2020
Autism spectrum disorder (ASD) is a complex disorder with an unclear aetiology and an estimated global prevalence of 1%. However, studies of ASD in the Vietnamese population are limited.
Bui, HTP, Dao, LTM, Do, DH, Ha, LT, Le, HTT, Le, VS, Ly, HTT, Mukhopadhyay, A, Nguyen, HT, Nguyen, HT, Nguyen, LT, Tran, KT, Vu, DM   +12 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

ELK1 inhibition alleviates amyloid pathology and memory decline by promoting the SYVN1-mediated ubiquitination and degradation of PS1 in Alzheimer’s disease

Experimental and Molecular Medicine
ELK1 is a member of the E-twenty-six transcription factor family and is usually activated by phosphorylation at Ser383 and Ser389 by extracellular signal-regulated kinase 1/2 (ERK1/2).
Lilin Yi, Junjie Li, Yan He, Jiaojiao Wang, Maoju Wang, Song Guo, Man Luo, Bin Wu, Mingliang Xu, Qiuyun Tian, Yepeng Fan, Mulan Chen, Boqing Xu, Lei Xia, Weihong Song, Guiqiong He, Yehong Du, Zhifang Dong   +17 more
doaj   +1 more source

Neurobiological abnormalities in the first few years of life in individuals later diagnosed with Autistic Spectrum Disorder : A review of recent data [PDF]

, 2014
Peer reviewedPublisher ...
Allely, C.S., Gillberg , C, Wilson, P.
core   +6 more sources

Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment

, 2014
The Hair Follicle (HF) is a vital component of mammalian skin and represents a unique, highly regenerative system that undergoes phases of rapid growth, regression, and resting periods. The hair cycling is of profound clinical relevance since majority of
Marijana ViÄiÄ, I. Brajac, Darinka Periša, M. Kaštelan   +3 more
semanticscholar   +1 more source

The Role of Early Growth Response 1 (EGR1) in Brain Plasticity and Neuropsychiatric Disorders

Frontiers in Behavioral Neuroscience, 2017
It is now clearly established that complex interactions between genes and environment are involved in multiple aspects of neuropsychiatric disorders, from determining an individual’s vulnerability to onset, to influencing its response to therapeutic ...
Florian Duclot, M. Kabbaj
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Differences in catch-up growth and its relationship to nutritional status between SGA and AGA twins and singletons in the first year after birth: a prospective cohort study

Scientific Reports
To compare the difference between appropriate for gestational age (AGA) and small for gestational age (SGA) of singleton and twin in terms of catch-up growth (CUG) and nutritional status in the first year after birth through a prospective cohort study. A
Minghui Xiong, Ting Pan, Zhanzhan Zhang, Yuanfeng Zhong, Qian Chen, Yannan Wan, Lin Zhu, Li Chen, Xuan Zhang   +8 more
doaj   +1 more source

TFE3-mediated neuroprotection: Clearance of aggregated α-synuclein and accumulated mitochondria in the AAV-α-synuclein model of Parkinson's disease

Genes and Diseases
Parkinson's disease (PD) is a neurodegenerative disorder characterized by fibrillar neuronal inclusions containing aggregated α-synuclein (α-Syn). While the pathology of PD is multifaceted, the aggregation of α-Syn and mitochondrial dysfunction are well ...
Xin He, Mulan Chen, Yepeng Fan, Bin Wu, Zhifang Dong   +4 more
doaj   +1 more source