Results 171 to 180 of about 10,050,077 (365)

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Nutritional status and access to clean fuels: Evidence from South Asia [PDF]

open access: yes
Indoor air pollution due to solid fuels is among the ten most important risk factors in global burden of disease leading to respiratory diseases, anaemia, blindness and other disorders.
Bhagowalia, Priya, Gupta, Parul
core   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

865 NUTRITION AND POOR GROWTH IN PRE-ADOLESCENT CHILDREN WITH SICKLING DISORDERS [PDF]

open access: bronze, 1981
Marie O Russell   +5 more
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Developmental Skills of Children with and Without Congenital Hypothyroidism

open access: yesIranian South Medical Journal, 2020
Background: Congenital hypothyroidism is one of the most common endocrinology diseases in children. Given the importance of evaluating the normal growth and development and identifying growth and development abnormalities, this study aimed to evaluate ...
Belghes Rovshan   +3 more
doaj  

ADVANTAGES OF THE hGH 24hr SECRETORY PATTERN IN DISTINGUISHING GROWTH DISORDERS [PDF]

open access: bronze, 1988
R Keret   +4 more
openalex   +1 more source

Growth Disorders [PDF]

open access: yesMedical Journal Armed Forces India, 2003
openaire   +2 more sources

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Dangers of Youth Sport Specialization [PDF]

open access: yes, 2018
Year-round training in a single sport is increasingly common among youth athletes. Contributing factors may include external pressures, early recruiting, pursuit of scholarships, and private leagues.Risks may include: overuse injuries, muscle imbalances,
Doveri, Marisa P., Neuffer, Jenica R.
core   +1 more source

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