Results 51 to 60 of about 1,494,529 (338)

Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs. [PDF]

, 2019
Proper axonal growth and guidance is essential for neuron differentiation and development. Abnormal neuronal development due to genetic or epigenetic influences can contribute to neurological and mental disorders such as Down syndrome, Rett syndrome, and
Almenar-Queralt, Angels, DerMardirossian, Celine, Head, Brian P, Leem, Joseph, Patel, Hemal H, Patel, Piyush M, Roth, David M, Wang, Shanshan, Zhang, Zheng   +8 more
core   +1 more source

Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]

, 2015
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA, Quartini, Adele, Tirassa, Paola   +2 more
core   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment. [PDF]

, 2017
Sequencing studies have implicated haploinsufficiency of ARID1B, a SWI/SNF chromatin-remodeling subunit, in short stature (Yu et al., 2015), autism spectrum disorder (O'Roak et al., 2012), intellectual disability (Deciphering Developmental Disorders ...
Araujo, Attanasio, Basu, Boldrini, Bonneh, Brautbar, Castro, DeCarolis, Deciphering Developmental Disorders Study, Greco, Halgren, Harrow, Ho, Hoyer, Imai, Ka, Kadoch, Kanner, Katayama, Kim, Kletzl, Konopka, Lein, Li, Liao, O'Roak, Persson, Robinson, Ronan, Santen, Santen, Santen, Schmaal, Schrier Vergano, Silverman, Sim, Travis, Tropea, Tsurusaki, Walker, Wieczorek, Yu   +41 more
core   +1 more source

Phenotypic characteristics and rehabilitation effect of children with regressive autism spectrum disorder: a prospective cohort study

BMC Psychiatry
Background In this prospective cohort study, we determined the phenotypic characteristics of children with regressive autism spectrum disorder (ASD) and explored the effects of rehabilitation.
Chaoqun Hu, Ting Yang, Jie Chen, Ying Dai, Hua Wei, Qionghui Wu, Hongyu Chen, Dan Long, Yuru Feng, Qiuhong Wei, Qian Zhang, Li Chen, Tingyu Li   +12 more
doaj   +1 more source

Chicken floss and catfish nuggets supplementary to increasing weight gain in stunted children

Medisains, 2023
Background: Stunted children are not only less tall, but most of them are also underweight. Lack of nutritional intake, especially protein intake, is suspected as one of the factors.
Krisdiana Wijayanti, Bekti Putri Harwijayanti, Murti Ani   +2 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Parental Anthropometric Indices and Obesity in Children

Acta Medica Iranica, 2016
The aim of this study was to investigate the correlation between each parent’s Body Mass Index (BMI) and maternal age with weight status of children. This was an analytic cross-sectional study which was conducted on 12-year-old students from different ...
Shahin Koomanaee, Manijeh Tabrizi, Novin Naderi, Afagh Hassanzadeh Rad, Kobra Boloky Moghaddam, Setila Dalili   +5 more
doaj  

Comparison of the prevalence and trend of malnutrition between 0–6 years and 7–11 years old Iranian children: A systematic review and meta-analysis

International Journal of Preventive Medicine, 2020
Background: To plan for decreasing the prevalence of malnutrition among children, reliable data of current status are required. The aim of the present cross-sectional study was to estimate the prevalence and trend of malnutrition among Iranian children ...
Fatemeh Azizi-Soleiman, Hamid Sharifi, Maryam Zamanian   +2 more
doaj   +1 more source

Evaluating the TUITEK® patient support program in supporting caregivers of children diagnosed with growth hormone deficiency in Argentina

Frontiers in Endocrinology, 2023
IntroductionThe appropriate use of recombinant human growth hormone (r-hGH) treatment provides an opportunity to improve growth outcomes among pediatric patients with growth hormone deficiency (GHD).
Aria Reza Assefi, Selina Graham, María Lourdes Crespo, Matías Debicki, Jonathan Reston, Judit Gonzalez, Amrit Jheeta, Ekaterina Koledova   +7 more
doaj   +1 more source