Results 11 to 20 of about 6,896,550 (362)

An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular
Mei-Yu Quan   +16 more
doaj   +1 more source

Utilizing the ABC Transporter for Growth Factor Production by fleQ Deletion Mutant of Pseudomonas fluorescens

open access: yesBiomedicines, 2021
Pseudomonas fluorescens, a gram-negative bacterium, has been proven to be a capable protein manufacturing factory (PMF). Utilizing its ATP-binding cassette (ABC) transporter, a type I secretion system, P. fluorescens has successfully produced recombinant
Benedict-Uy Fabia   +4 more
doaj   +1 more source

Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
doaj   +1 more source

Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors [PDF]

open access: yes, 1992
Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula. In contrast,
Alessandro Azzarone   +28 more
core   +1 more source

Growth and Growth Factors [PDF]

open access: yes, 2008
The last year has again seen some major advances in the Growth and Growth Factors field. Significant advances have been made in our understanding of the genetics of growth. For example, mutations in the pericentrin gene PCNT are associated with both primordial dwarfism and Seckel syndrome.
Mehul T. Dattani, Evelien F. Gevers
openaire   +3 more sources

Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]

open access: yes, 2010
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V.   +2 more
core   +2 more sources

Growth and Growth Factors [PDF]

open access: yes, 2005
SOCS2 inactivation, which leads to growth hormone hypersensitivity and overgrowth, is selected as the mechanism of the year in this chapter. The second paper shows that PPAR plays a role in the growth of male mice. Under new paradigms, we learn that the disruption of a paternally expressed gene from the Gnas locus, XL s, is associated with poor ...
Régis Coutant, Natacha Bouhours-Nouet
openaire   +2 more sources

Pertumbuhan Bibit Kakao (Theobroma cacao L.) pada Berbagai Jenis Klon dan Jenis Pupuk Kandang

open access: yesJurnal Agro Industri Perkebunan, 2021
Several factors that affect production of cocoa (Theobroma cacao L.), one of which is the quality of seedlings. The quality of seedlings is affected by the type of clones and the composition of the planting media.
Leni Sri Widyastuti   +2 more
doaj   +1 more source

Epidermal Growth Factor

open access: yesAnnual Review of Biochemistry, 1972
During the course of the studies on the nerve growth factor of the submaxillary gland of the male mouse (1), it was observed that extracts of these glands, when injected into newborn mice, caused precocious opening of the eyelid and eruption of the incisors. A polypeptide responsible for this effect has been isolated (2).
Graham Carpenter, S Cohen
openaire   +9 more sources

Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]

open access: yes, 2017
The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert   +3 more
core   +2 more sources

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