Results 11 to 20 of about 6,896,550 (362)
An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness
Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular
Mei-Yu Quan+16 more
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Pseudomonas fluorescens, a gram-negative bacterium, has been proven to be a capable protein manufacturing factory (PMF). Utilizing its ATP-binding cassette (ABC) transporter, a type I secretion system, P. fluorescens has successfully produced recombinant
Benedict-Uy Fabia+4 more
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Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
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Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors [PDF]
Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula. In contrast,
Alessandro Azzarone+28 more
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Growth and Growth Factors [PDF]
The last year has again seen some major advances in the Growth and Growth Factors field. Significant advances have been made in our understanding of the genetics of growth. For example, mutations in the pericentrin gene PCNT are associated with both primordial dwarfism and Seckel syndrome.
Mehul T. Dattani, Evelien F. Gevers
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Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V.+2 more
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Growth and Growth Factors [PDF]
SOCS2 inactivation, which leads to growth hormone hypersensitivity and overgrowth, is selected as the mechanism of the year in this chapter. The second paper shows that PPAR plays a role in the growth of male mice. Under new paradigms, we learn that the disruption of a paternally expressed gene from the Gnas locus, XL s, is associated with poor ...
Régis Coutant, Natacha Bouhours-Nouet
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Pertumbuhan Bibit Kakao (Theobroma cacao L.) pada Berbagai Jenis Klon dan Jenis Pupuk Kandang
Several factors that affect production of cocoa (Theobroma cacao L.), one of which is the quality of seedlings. The quality of seedlings is affected by the type of clones and the composition of the planting media.
Leni Sri Widyastuti+2 more
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During the course of the studies on the nerve growth factor of the submaxillary gland of the male mouse (1), it was observed that extracts of these glands, when injected into newborn mice, caused precocious opening of the eyelid and eruption of the incisors. A polypeptide responsible for this effect has been isolated (2).
Graham Carpenter, S Cohen
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Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]
The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert+3 more
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