Single Cell Center of Mass for the Analysis of BMP Receptor Heterodimers Distributions
Journal of Imaging, 2021 At the plasma membrane, transmembrane receptors are at the interface between cells and their environment. They allow sensing and transduction of chemical and mechanical extracellular signals.
Hendrik Boog +2 more
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Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer
Frontiers in Oncology, 2021 Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive human malignancy and intrinsically resistant to conventional therapies. YAP1, as a key downstream effector of the Hippo pathway, plays an important role in tumorigenesis including PDAC ...
Chao Gao +14 more
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Cancer Medicine, 2023 Epithelium‐specific ETS transcription factor 1 (ESE1) has been implicated in epithelial homeostasis, inflammation, as well as tumorigenesis, and cancer progression.
Hui‐Jing Xu +12 more
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FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes
Frontiers in Cell and Developmental Biology, 2021 Adipocytes not only function as energy depots but also secrete numerous adipokines that regulate multiple metabolic processes, including lipid homeostasis.
Yu-Qing Lv +8 more
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FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress
Molecular Medicine, 2022 Background Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), are devastating clinical disorders with high mortality, and for which more effective therapies are urgently needed.
Qhaweni Dhlamini +11 more
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Cells, 2022 Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with dire consequences and in urgent need of improved therapies. Compelling evidence indicates that damage or dysfunction of AT2s is of central importance in the development ...
Yu-Qing Lv +12 more
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Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]
International Neurourology Journal, 2020 Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
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FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency
Frontiers in Cell and Developmental Biology, 2020 Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for their two unique characteristics: the ability to give rise to all somatic ...
Majid Mossahebi-Mohammadi +4 more
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Glutathione and IGF-1 in bovine seminal cryopreservation: oxidative stress response and pregnancy rate [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 The objective of this study was to evaluate the rate of conception, metabolic, and structural conditions of cryopreserved bovine sperm cells, plus extender with IGF-1 and glutathione (GSH).
D.S. Almeida +7 more
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An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness
Frontiers in Cell and Developmental Biology, 2020 Cancer stemness is associated with high malignancy and low differentiation, as well as therapeutic resistance of tumors including pancreatic ductal adenocarcinoma (PDAC). Fibroblast growth factors (FGFs) exert pleiotropic effects on a variety of cellular
Mei-Yu Quan +16 more
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