Results 21 to 30 of about 19,151,642 (313)

The biology of vascular endothelial growth factor.

open access: yesEndocrine reviews, 1997
The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1.
N. Ferrara, T. Davis-Smyth
semanticscholar   +1 more source

Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
doaj   +1 more source

Targeting Growth Factor and Cytokine Pathways to Treat Idiopathic Pulmonary Fibrosis

open access: yesFrontiers in Pharmacology, 2022
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin that usually results in death from secondary respiratory failure within 2–5 years of diagnosis.
Hongbo Ma   +7 more
doaj   +1 more source

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

open access: yesCancers, 2017
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar   +1 more source

The Fibroblast Growth Factor signaling pathway

open access: yesWiley Interdisciplinary Reviews: Developmental Biology, 2015
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF receptors (FGFRs).
D. Ornitz, N. Itoh
semanticscholar   +1 more source

In Vitro Characterization of Hypoxia Preconditioned Serum (HPS)—Fibrin Hydrogels: Basis for an Injectable Biomimetic Tissue Regeneration Therapy

open access: yesJournal of Functional Biomaterials, 2019
Blood-derived growth factor preparations have long been employed to improve perfusion and aid tissue repair. Among these, platelet-rich plasma (PRP)-based therapies have seen the widest application, albeit with mixed clinical results to date.
Ektoras Hadjipanayi   +15 more
doaj   +1 more source

Sequential Delivery of Dual Growth Factors from Injectable Chitosan-Based Composite Hydrogels

open access: yesMarine Drugs, 2019
Local administration of platelet-derived growth factor-BB (PGDF-BB) and bone morphogenetic protein-2 (BMP-2) in a sequential release manner could substantially promote bone healing.
Qing Min   +5 more
doaj   +1 more source

Growth factors and goitrogenesis [PDF]

open access: yesJournal of Endocrinology, 1999
By combining data from studies of multinodular non-toxic goitre (MNTG) with data from rat models of goitre induction and in vitro models, a map of the growth factors involved in goitrogenesis has been constructed. We have addressed the roles of the insulin-like growth factors, transforming growth factors, fibroblast growth factors, endothelins, etc. We
Bidey, S. P., Hill, D. J., Eggo, M. C.
openaire   +4 more sources

Current insights on use of growth factors as therapy for Intervertebral Disc Degeneration

open access: yesBiomolecular Concepts, 2018
Chronic low back pain is a critical health problem and a leading cause of disability in aging populations. A major cause of low back pain is considered to be the degeneration of the intervertebral disc (IVD). Recent advances in therapeutics, particularly
Kennon Justin C.   +4 more
doaj   +1 more source

Neuroprotection: Pro-survival and Anti-neurotoxic Mechanisms as Therapeutic Strategies in Neurodegeneration

open access: yesFrontiers in Cellular Neuroscience, 2019
Neurotrophins (NTs) are a subset of the neurotrophic factor family. These growth factors were originally named based on the nerve growth functional assays used to identify them. NTs act as paracrine or autocrine factors for cells expressing NT receptors.
Horacio Uri Saragovi   +7 more
doaj   +1 more source

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