Results 61 to 70 of about 6,896,550 (362)

Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]

, 2017
Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas, Blahut, Johnathon, Borkovich, Katherine A, Cabrera, Ilva E, Carrera, Cristian, Carrillo, Alexander J, Chen, Vivian, Clark, Isaiah, Dietrich, Sarah, Fierro, Gerardo, Ganzen, Logan, Mei, Jennifer, Orellana, Jose, Prudhomme, Loren, Schacht, Patrick, Wise, Shelby, Yang, Kevin, Zhong, Hui   +17 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Bone morphogenetic proteins: Signaling periodontal bone regeneration and repair

Journal of Pharmacy and Bioallied Sciences, 2016
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal ...
G Sai Anusuya, M Kandasamy, S A Jacob Raja, S Sabarinathan, P Ravishankar, Balu Kandhasamy   +5 more
doaj   +1 more source

Cytokines and growth factors cross-link heparan sulfate [PDF]

Open Biology, 2015
The glycosaminoglycan heparan sulfate (HS), present at the surface of most cells and ubiquitous in extracellular matrix, binds many soluble extracellular signalling molecules such as chemokines and growth factors, and regulates their transport and ...
Elisa Migliorini, Dhruv Thakar, Jens Kühnle, Rabia Sadir, Douglas P. Dyer, Yong Li, Changye Sun, Brian F. Volkman, Tracy M. Handel, Liliane Coche-Guerente, David G. Fernig, Hugues Lortat-Jacob, Ralf P. Richter   +12 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma [PDF]

, 2018
Rationale:Small bowel adenocarcinoma (SBA) is an uncommon gastrointestinal cancer, thus limited data about treatment for advanced disease are available.
Anselmi, Elisabetta, Falcone, Rosa, Filetti, Marco, Marchetti, Paolo, Roberto, Michela   +4 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Growth factor for influenza bacteria

California Agriculture, 1961
California Agriculture - All ...
California Agriculture
doaj  

Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort [PDF]

, 2019
Background: Epidermal growth factor receptor (EGFR) is a member of the ErbB family of tyrosine kinase receptor proteins that plays important roles in tumour cell survival and proliferation.
Abdul Raub, Sayyidi Hamzi, Azhari, Azlah Kamilah, Eswaran, Jeyanthy, Soundararajan, Meera, Syed Husain, Sharifah Noor Akmal, Wan Hasan, Wan Atiqah Najiah, Zakaria, Zubaidah, Zulkifle, Muhamad Farid   +7 more
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source