Results 251 to 260 of about 6,173,170 (321)
Some of the next articles are maybe not open access.
Genetic defects of the growth hormone-insulin-like growth factor axis.
Trends in Endocrinology & Metabolism, 2000Our understanding of the physiology of the growth hormone-insulin-like growth factor (GH-IGF) axis has been characterized by remarkable advances in the past decade, with clarification of genetic defects in the development of somatotropes, GH secretion and action, and IGF synthesis and action.
A. López-Bermejo +2 more
semanticscholar +3 more sources
Effects of renal failure on the growth hormone-insulin-like growth factor axis.
The Journal of Pediatrics, 1997Children with chronic renal failure (CRF) often have retarded growth, and abnormalities of the growth hormone-insulin-like growth factor (GH-IGF) axis in CRF may contribute to this growth failure. The serum GH and IGF levels are normal in these children, but IGF bioactivity is low as a result of excess IGF binding proteins (IGFBPs) in the 35 kd serum ...
David R. Powell
semanticscholar +3 more sources
Fetal programming of the growth hormone–insulin-like growth factor axis
Trends in Endocrinology and Metabolism, 2002Richard Holt
exaly +2 more sources
Osteoporosis and the Growth Hormone-Insulin-Like Growth Factor Axis
Hormone Research in Paediatrics, 2002Osteoporosis is the result of an imbalance between bone resorption and bone formation. Currently, mainly drugs that inhibit bone resorption are available for the treatment of osteoporosis. A new approach in the treatment of osteoporosis is the use of anabolic agents that increase bone turnover, both bone formation and resorption.
Piet P M M, Geusens, Steven, Boonen
openaire +2 more sources
Growth hormone, insulin‐like growth factor I, and motoneuron size
Journal of Neurobiology, 1997In this study we asked whether growth hormone (GH) and one of its key mediators, insulin-like growth factor I (IGF-I), influence spinal motoneuron size in conjunction with whole body size. We present evidence that GH has such a role, possibly without the mediation of IGF-I.
L, Chen +4 more
openaire +2 more sources
The growth hormone insulin-like growth factor axis in kidney revisited
American Journal of Physiology-Renal Physiology, 1993Studies characterizing actions of growth hormone (GH) and insulin-like growth factors (IGF) in kidneys of adult and developing animals and humans have provided a good deal of insight into the functions of these peptides. Although certain of the actions may be mediated directly by GH, most appear to result from effects of GH to increase levels of ...
M R, Hammerman, S B, Miller
openaire +2 more sources
Aging and the growth hormone/insulin like growth factor-I axis
Pituitary, 2007Growth hormone release and IGF-I synthesis decrease with increasing age. The regulation of the GH/IGF-I system is dependent on the integrity of the hypothalamus, pituitary and liver. During aging there are several changes which contribute to the decline in GH/IGF-I including changes in signal to the somatotrophs from growth hormone releasing hormone ...
Mark, Sherlock, Andrew A, Toogood
openaire +2 more sources
Growth hormone/insulin-like growth factors and hematopoiesis
2002Abstract The growth hormone/insulin-like growth factor (GH/IGF) system plays an essential role in cell growth and tissue differentiation during development. However, the role of GH/IGF-I in the regulation of production of red blood cells, is not completely understood. Erythropoiesis is regulated mainly by erythropoietin.
Robert Moghaddas, Robert Rapaport
openaire +1 more source
The role of growth hormone/insulin-like growth factors in adipocyte differentiation
Metabolism, 1995Growth of the adipose tissue results from both the enlargement of mature adipocytes and the formation of new adipocytes from adipocyte precursor cells. The differentiation process of adipocyte precursor cells is controlled by a variety of hormones. Clinical observations indicate that growth hormone (GH) and insulin-like growth factor I (IGF-I) are able
M, Wabitsch +3 more
openaire +2 more sources
Exercise and the Growth Hormone—Insulin-Like Growth Factor-1 Axis
2000Naturally occurring physical activity in humans plays a profound role in tissue anabolism, growth, and development, yet little is known about the mechanisms that link patterns of exercise with tissue anabolism. Anabolic effects of exercise are not limited to individuals engaged in competitive sports who are particularly focused on improvements in ...
Alon Eliakim +2 more
openaire +1 more source