Results 111 to 120 of about 182,947 (342)
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Advanced Healthcare Materials, EarlyView.This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source
eLife, 2013 We examine the impact of targeted disruption of growth hormone-releasing hormone (GHRH) in mice on longevity and the putative mechanisms of delayed aging.
Liou Y Sun +9 more
doaj +1 more source
Long-term Infusion of Growth Hormone Release Inhibiting Hormone in Acromegaly: Effects on Pituitary and Pancreatic Hormones [PDF]
, 1974 G. M. Besser +11 more
openalex +1 more source
Growth hormone-releasing peptide and its analogues
Trends in Endocrinology & Metabolism, 1995 GHRPs are oligopeptides with GH-releasing effects in humans when given by either parenteral or oral routes; in addition, nonpeptide pharmacologic analogues have recently been synthesized. Although the exact mechanism of action of these agents has not been fully established, there is probably a dual site of action on both the pituitary and the ...
Korbonits, M, Grossman, AB
openaire +3 more sources
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Frontiers in Physiology, 2014 Rationale. Antibiotic treatment of patients infected with G- or G+ bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs.
Istvan eCzikora +21 more
doaj +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
Advanced Healthcare Materials, EarlyView.A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages [PDF]
, 2013 Two recently cloned gonadotropin-releasing hormone (GnRH) receptors (lamprey GnRH-R-2 and lamprey GnRH-R-3) along with lamprey (l) GnRH-R-1 were shown to share similar structural features and amino acid motifs common to other vertebrate receptors.
Daukss, Dana M. +3 more
core +1 more source
Pilot Study of Growth Hormone Release in Sleep of the Chair-Adapted Baboon: Potential as Model of Human Sleep Release [PDF]
, 1972 DONAL C. PARKER +4 more
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Advanced Healthcare Materials, EarlyView.This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An +8 more
wiley +1 more source