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This study identifies reduced taurine availability as a mediator of intermittent fasting in colorectal cancer and shows that taurine interacts with GRP78 to maintain PERK abundance post‐transcriptionally. It further shows that taurine depletion destabilizes PERK, induces immunogenic paraptosis, remodels the tumor microenvironment toward a CD8+ T cell ...
Baohui Song +11 more
wiley +1 more source
Lactate Signal: Modulator of Cellular Energy Production and Anabolism
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley +1 more source
Benign prostatic hyperplasia often affects aging men. Antagonists of the neuropeptide growth hormone-releasing hormone reduced prostate weight in an androgen induced benign prostatic hyperplasia model in rats.
Ferenc Rick, Mehrdad Nadji
exaly +2 more sources
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Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis
Trends in Endocrinology and Metabolism, 2002Rhonda D Kineman, Lawrence A. Frohman
exaly
Molecular and functional analyses of growth hormone-releasing hormone (GHRH) from olive flounder ()
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2011Woo-Jin Kim, Bo-Hye Nam, Sang-Jun Lee
exaly
Growth hormone response to growth hormone releasing hormone in depression and schizophrenia
Psychiatry Research, 1990Andrew R Hoffman, J G Csernansky
exaly
Low growth hormone response to growth hormone–releasing hormone in child depression
Biological Psychiatry, 2000Boris Birmaher +2 more
exaly

