Neuroprotective actions of ghrelin and growth hormone secretagogues [PDF]
The brain incorporates and coordinates information based on the hormonal environment, receiving information from peripheral tissues through the circulation.
Laura M. Frago +14 more
doaj +7 more sources
Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy [PDF]
IntroductionGrowth hormone secretagogues (GHSs) exert multiple actions, being able to activate GHS-receptor 1a, control inflammation and metabolism, to enhance GH/insulin-like growth factor-1 (IGF-1)-mediated myogenesis, and to inhibit angiotensin ...
Brigida Boccanegra +20 more
doaj +4 more sources
Elizabeth C Hersch, George R MerriamVA Puget Sound Health Care System and University of Washington School of Medicine, Tacoma and Seattle, Washington USAAbstract: Although growth hormone (GH) is primarily associated with linear growth in childhood, it ...
Elizabeth C Hersch, George R Merriam
doaj +3 more sources
The synthesis of a small library of prospective growth hormone secretagogues [PDF]
Employing tools of combinatorial chemistry, an original methodological approach has been developed and applied for the design and synthesis of a small library of peptide-like compounds, prospective growth hormone (GH) secretagogues.
Pejović Vojislav +2 more
doaj +4 more sources
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration [PDF]
Performance-enhancing drugs (PEDs) marketed as “research compounds” include unregulated peptides intended to modulate the growth hormone–insulin-like growth factor-1 (GH–IGF-1) axis.
Aleksander Dominikowski +5 more
doaj +2 more sources
Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. [PDF]
BackgroundIschemic heart disease is a leading cause of mortality. To study this disease, ischemia/reperfusion (I/R) models are widely used to mimic the process of transient blockage and subsequent recovery of cardiac coronary blood supply.
Yi Ma +4 more
doaj +2 more sources
The Safety and Efficacy of Growth Hormone Secretagogues. [PDF]
Growth hormone (GH) increases lean body mass, decreases fat mass, increases exercise tolerance and maximum oxygen uptake, enhances muscle strength, and improves linear growth. Long-term studies of GH administration offer conflicting results on its safety, which has led to strict Food and Drug Administration criteria for GH use.
Sigalos JT, Pastuszak AW.
europepmc +4 more sources
Potential Applications for Growth Hormone Secretagogues Treatment of Amyotrophic Lateral Sclerosis. [PDF]
Meanti R +9 more
europepmc +2 more sources
Could Overt Diabetes Be Triggered by Abuse of Selective Androgen Receptor Modulators and Growth Hormone Secretagogues? A Case Report and Review of the Literature. [PDF]
Sotorník R, Suissa R, Ardilouze JL.
europepmc +2 more sources
Growth Hormone Secretagogues and the Regulation of Calcium Signaling in Muscle. [PDF]
Bresciani E +6 more
europepmc +2 more sources

