Results 21 to 30 of about 6,358 (191)

Impact of growth hormone (GH) deficiency and GH replacement upon thymus function in adult patients. [PDF]

PLoS ONE, 2009
Despite age-related adipose involution, T cell generation in the thymus (thymopoiesis) is maintained beyond puberty in adults. In rodents, growth hormone (GH), insulin-like growth factor-1 (IGF-1), and GH secretagogues reverse age-related changes in ...
Gabriel Morrhaye, Hamid Kermani, Jean-Jacques Legros, Frederic Baron, Yves Beguin, Michel Moutschen, Remi Cheynier, Henri J Martens, Vincent Geenen   +8 more
doaj   +1 more source

Intracerebroventricular Administration of Growth Hormone Releasing Peptide-6 (GHRP-6) Inhibits Food Intake, but not Food Retention of Crop and Stomach in Neonatal Chicks

The Journal of Poultry Science, 2006
Growth hormone secretagogues (GHS), including ghrelin, are known to stimulate feeding behavior in mammals. In contrast, intracerebroventricular (ICV) injection of rat or chicken ghrelin, strongly inhibits food intake in chicks.
Md. Sakirul Islam Khan, Koh-Ichi Dodo, Kazuki Yahata, Sayuri Nishimoto, Hiroshi Ueda, Tetsuro Taneike, Takio Kitazawa, Yoshinao Hosaka, Takashi Bungo   +8 more
doaj   +1 more source

Ghrelin axis genes, peptides and receptors : recent findings and future challenges [PDF]

, 2011
The ghrelin axis consists of the gene products of the ghrelin gene (GHRL), and their receptors, including the classical ghrelin receptor GHSR. While it is well-known that the ghrelin gene encodes the 28 amino acid ghrelin peptide hormone, it is now also ...
Seim, Inge, Josh, Peter, Cunningham, Peter, Herington, Adrian, Chopin, Lisa K.   +4 more
core   +2 more sources

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium [PDF]

, 2013
Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such
A Gnoni, A Pace, A Sharma, AJ Hietaranta, AK Saluja, AK Saluja, AS Gukovskaya, B Han, B Han, B Hofbauer, B Kruger, C Schafer, Catherine J. Baty, CH Kubisch, Chandra Durgampudi, Chathur Acharya, DN Criddle, Donna B. Stolz, EC Thrower, EM Parker, F Gorelick, F Mooren, F Nozu, G Lynch, H Weber, HK Baumgartner, I Gukovsky, I Gukovsky, I Samuel, JA Tapia, JA Williams, Jenny Karlsson, JV Gerasimenko, KA Muili, Krutika Patel, L Fischer, L Orlichenko, Lidiya Orlichenko, LJ Christopher, LJ Lombardo, LS Orlichenko, M Sendler, MS O'Konski, OA Mareninova, OH Petersen, Pawan Noel, PC Redondo, Rachel Cline, Ram Narayan Trivedi, RD Duan, RR Torgerson, RR Torgerson, S Kawabata, S Navina, Sarah Navina, SD Waterford, SG Weller, SJ Pandol, Sohail Z. Husain, Stuart E. Dryer, SZ Husain, SZ Husain, T Eley, T Grady, T Grady, V Sancho, Vijay P. Singh, Vivek Mishra, VP Singh, VP Singh, VP Singh, VP Singh, Y Tsunoda   +72 more
core   +2 more sources

Growth Hormone-Releasing Hormone in Diabetes

Frontiers in Endocrinology, 2016
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand, Natalia A Tamarina, Andrew V Schally, Louis H Philipson   +3 more
doaj   +1 more source

The growth hormone secretagogue receptor

Growth Hormone & IGF Research, 1999
The specific human growth hormone (GH) secretagogue receptor (type la) was cloned in 1996 using the nonpeptide GH secretagogue MK-0677 as a ligand. 1,2 It belongs to the G-protein coupled seven transmembrane domain receptor family, but does not show close homology with any of the known subgroups of receptors, though its sequence is conserved between ...
KORBONITS M., CICCARELLI E., GHIGO, Ezio, GROSSMAN AB   +3 more
openaire   +3 more sources

Effects of suramin on hormone release by cultured rat anterior pituitary cells [PDF]

, 1990
Suramin is a polyanionic compound which has been used in the treatment of trypanosomiasis and acquired immunodeficiency syndrome (AIDS), while preliminary success ...
Abou-Hashim, E.M. (Ekbal), El-Kannishy, M.H. (Mohammed), Hofland, L.J. (Leo), Holder, F.H. (Fred) den, Jong, F.H. (Frank) de, Koetsveld, P.M. (Peter) van, Lamberts, S.W.J. (Steven), Marzouk, H.F.A.I. (Hamdy), Steenbergen, J. (Jacobie), Zuiderwijk, J.M. (Joke)   +9 more
core   +1 more source

Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect [PDF]

, 2009
[Abstract] The first “growth hormone secretagogues” (GHSs) were discovered by Bowers et al. in 1977. In 1996 the GHSs receptor (GHS-R 1a) was cloned. The endogenous ligand for this receptor, ghrelin, was not identified until 1999.
Cordido, Fernando, Isidro, María Luisa, Nemina, Rosa, Sangiao-Alvarellos, Susana   +3 more
core   +2 more sources

Comparative proteomic analysis of growth hormone secretagogue A233 treatment of murine macrophage cells J774A.2 indicates it has a role in antiviral innate response

Biochemistry and Biophysics Reports, 2016
Background: Growth hormone secretagogues (GHS), among other factors, regulate the release of GH. The biological activity of the secretagogue peptide A233 as a promoter of growth and innate immunity in teleost fish has previously been demonstrated, but ...
Rebeca Martínez, Teresa Núñez de Villavicencio-Díaz, Aniel Sánchez, Yassel Ramos, Jesús Noda Ferro, Lázaro Gil González, Milagros Méndez, Elsa Rodríguez, Ernesto Marcos, Belinda Sánchez, Yordanka Masforrol, Hilda Garay, Fernando Albericio, Lisset Hermida, Luis Javier González, Eva Vonasek, Mario P Estrada, Vladimir Besada   +17 more
doaj   +1 more source

Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]

, 2014
Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core   +2 more sources