Results 31 to 40 of about 5,558,251 (188)

Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels

American Journal of Men's Health, 2017
Realizing the reported misuse of human growth hormone (GH), investigation of a safe alternative mechanism for increasing endogenous GH is needed. Several GH secretagogues are available, including GH-releasing peptides (GHRPs) GHRP-2 and GHRP-6, and the ...
John T. Sigalos, Alexander W. Pastuszak, Andrew Allison, Samuel J. Ohlander, Amin Herati, Mark C. Lindgren, Larry I. Lipshultz   +6 more
doaj   +1 more source

Physicochemical, Functional, and Health‐Promoting Properties of Processed Nettle (Urtica Dioica) Leaves: A Review

Future Postharvest and Food, EarlyView.
Stinging nettle (Urtica dioica L.) leaves are a nutrient‐dense source of proteins, dietary fiber, chlorophylls, carotenoids, and phenolic compounds. Processing technologies enable the production of powders and extracts for incorporation into bakery, beverage, dairy, and nutraceutical products; however, challenges remain regarding sensory quality ...
Mary Nkongho Tanyitiku, Rakshya Pandit, Mihiri Vanniarachchy   +2 more
wiley   +1 more source

Effects of growth hormone and its secretagogues on bone

, 2001
The growth hormone (GH)/insulin-like growth factor-1 axis is not only of importance for linear body growth during childhood, but it is also one of the major determinants of adult bone mass. Studies show that GH treatment increases bone mass in rodents as
Ohlsson, Claes,, Jansson, John-Olov,, Svensson, Johan,, Lall, S, Ahnfelt-Rønne, I, Dickson, Suzanne L.,, Bengtsson, Bengt-Åke,, Rømer, J   +7 more
core   +1 more source

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario, Margarita Díaz‐Martínez, Mario Alberto Viazcan‐Carbajal, Victor David González‐Fernández   +3 more
wiley   +1 more source

Nutrient‐specific combinatorial secretion of GLP‐1 and neurotransmitters in the enteroendocrine L‐cell line GLUTag

The FEBS Journal, EarlyView.
Enteroendocrine L cells function as chemosensors in the intestine. Using the L‐cell line GLUTag, we show that distinct nutrients trigger different combinations of co‐secretion of GLP‐1 and neurotransmitters: D‐glucose evokes GLP‐1, glutamate, and ATP; L‐glutamine evokes GLP‐1 and glutamate; sucralose and butyrate evoke only GLP‐1.
Yo Ito, Kazuki Harada, Yuri Osuga‐Yoshiike, Masami Yokota Hirai, Tetsuya Kitaguchi, Takashi Tsuboi   +5 more
wiley   +1 more source

Pilot Study of a Herbal Formulation Composed of Bidens pilosa for Constipation in Humans

eFood, Volume 7, Issue 5, October 2026.
ABSTRACT The gut microbiota and their metabolites are associated with constipation and other gastrointestinal diseases. Dietary phytochemicals are crucial factors shaping gut microbiota. Here, we conducted a first‐in‐human trial of the herbal formulation BP, composed of a Bidens pilosa extract and excipient, in volunteers with constipation.
Tien‐Fen Kuo, Yi‐San Lee, Greta Yang, Yu‐Chuan Liang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Neuroregulation of the Hypothalamus-Pituitary-Adrenal (HPA) Axis in Humans: Effects of GABA-, Mineralocorticoid-, and GH-Secretagogue-Receptor Modulation

The Scientific World Journal, 2006
The hypothalamus-pituitary-adrenal (HPA) axis exerts a variety of effects at both the central and peripheral level. Its activity is mainly regulated by CRH, AVP, and the glucocorticoid-mediated feedback action.
Roberta Giordano, Micaela Pellegrino, Andreea Picu, Lorenza Bonelli, Marcella Balbo, Rita Berardelli, Fabio Lanfranco, Ezio Ghigo   +7 more
doaj   +1 more source

Ghrelin Alleviates Aging‐Related Cognitive Impairment by Regulating Autophagy‐Related Signaling via the SHBG/JNK1/Beclin1 Axis in Microglia

Aging Cell, Volume 25, Issue 10, October 2026.
This study found that aging‐related cognitive impairment is accompanied by hippocampal microglial senescence. Ghrelin suppresses microglial senescence by promoting autophagy through the SHBG/JNK1/Beclin1 axis, thereby alleviating aging‐related cognitive impairment. The graphical abstract was drawn using the Figdraw.
Lixing Zhou, Ying Cheng, Wanyu Zhao, Xuelian Sun, Fengjuan Hu, Meiling Ge, Yan Zhang, Gongchang Zhang, Birong Dong, Xiaolei Liu   +9 more
wiley   +1 more source

Growth hormone (GH)-independent stimulation of adiposity by GH secretagogues

, 2001
Growth hormone secretagogues (GHSs) stimulate growth hormone (GH) secretion, which is lipolytic. Here we compared the effects of twice daily s.c. treatment of GH and the GHS, ipamorelin, on body fat in GH-deficient (lit/lit) and in GH-intact (+/lit and +/
Ohlsson, Claes,, Jansson, John-Olov,, Lall, S, Tung, L Y, Dickson, Suzanne L.,   +4 more
core   +1 more source

Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Early‐life exposure to metabolic hormones may influence the development of taste acceptance and subsequent intake of hyperpalatable foods (HPF) in infants, but evidence integrating hormonal, behavioral, and dietary data in humans is limited.
Ana Luz Kruger, Agustina Malpeli, Marisa Sala, Carla Casado, Ignacio Mendez, Lucrecia Fotia, Mercedes López, María Silvina Faquini, Daniel Castrogiovanni, Helgi B. Schiöth, Sophie Nicklaus, Mario Perello, María F. Andreoli   +12 more
wiley   +1 more source