Results 211 to 220 of about 144,578 (260)

Dosing of Growth Hormone in Growth Hormone Deficiency

Hormone Research in Paediatrics, 1999
Growth hormone (GH) treatment of GH-deficient (GHD) children is to a certain extent standardized worldwide. Recombinant 22 kDa GH is injected once daily by the subcutaneous route, mostly in the evening. The amount of GH injected (calculated per kg body weight or body surface area, expressed in terms of IU or mg) in prepubertal children mimics the known
M B, Ranke, R, Schweizer, H A, Wollmann, P, Schwarze   +3 more
openaire   +2 more sources

Growth hormone replacement for adult growth hormone deficiency

Expert Opinion on Pharmacotherapy, 2003
Growth hormone deficiency (GHD) in childhood causes growth retardation, short stature and significant impairment of adult height. Growth hormone (GH) has been given successfully to these children for > 40 years but only since the introduction of recombinant DNA technology, has enough GH been available for paediatric needs and also for other indications.
Ilan Shimon
exaly   +3 more sources

Growth hormone deficiency in the adult

Pituitary, 2006
Growth hormone deficiency (GHD) in adults may be of either adult or childhood onset and may occur as isolated GHD or as multiple hormone deficiencies. Adult-onset GHD (AoGHD) usually results from damage to the pituitary gland or hypothalamus. GH is frequently undetectable in normal subjects and thus GHD cannot be distinguished from the normal state ...
DOGA M, BONADONNA, Stefania, GOLA M, MAZZIOTTI, Gherardo, GIUSTINA, Andrea   +4 more
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Growth hormone deficiency in children

Pituitary, 2008
The foundation for the diagnosis of growth hormone (GH) deficiency in childhood must be auxology, that is, the comparison of the child's growth pattern to that of established norms for gender and ethnicity. It is only in those growing considerably more slowly than average that testing for GHD makes sense. Assessment of laboratory tests, whether static,
Erick J, Richmond, Alan D, Rogol
openaire   +2 more sources

Genetics of Growth Hormone Deficiency

Endocrinology and Metabolism Clinics of North America, 2007
When a child is not following the normal, predicted growth curve, an evaluation for underlying illness and central nervous system abnormalities is required and appropriate consideration should be given to genetic defects causing growth hormone (GH) deficiency.
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Isolated growth hormone deficiency

Pituitary, 2007
Isolated growth hormone deficiency (IGHD) represents conditions of GH deficiency that are not necessarily associated with other pituitary hormone deficiencies or with an organic lesion. Three sub-categories of IGHD have been clinically identified (IGHD types 1-3), and IGHD type 1 has been further separated into IGHD types 1a and b.
Libia M, Hernández, Phillip D K, Lee, Cecilia, Camacho-Hübner   +2 more
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Adult Growth Hormone Deficiency

Hormone Research, 2008
Several reports have focused on the clinical features of the untreated GH-deficient adult and the effect of GH therapy. The results reported are strikingly unanimous. Untreated GH-deficient adults have been shown to have increased cardiovascular mortality, reduced exercise capacity, reduced muscle strength, subnormal glomerular filtration rate and ...
J O, Jørgensen, J, Müller, J, Møller, T, Wolthers, N, Vahl, A, Juul, N E, Skakkebaek, J S, Christiansen   +7 more
openaire   +2 more sources

Diagnosis of Growth Hormone Deficiency

2010
The diagnosis of growth hormone deficiency (GHD) was essentially a clinical one prior to the advent of radioimmunoassay in the mid-1960s. From this point on both clinical and biochemical serum GH responses to a variety of provocation tests were used to define the condition. The definition of an adequate GH response to stimulation has changed over time,
E A, Webb, M T, Dattani
openaire   +2 more sources