Results 71 to 80 of about 5,558,251 (188)

Cardiovascular effects of ghrelin and growth hormone secretagogues

, 2008
Apart from promoting GH secretion and to regulate appetite and metabolism, it has become increasingly clear that GH secretagogues (GHS) and ghrelin exert a number of effects on the cardiovascular system.
Johansson, Inger,, Isgaard, Jörgen,, Barlind, Anna,   +2 more
core  

Cycloheximide blocks insulin-like growth factor I but not somatostatin inhibition of growth hormone secretion

, 1987
Growth hormone secretion is controlled by the two hypothalamic hormones, growth hormone releasing factor (GRF) and somatostatin. In addition, the insulin-like growth factors (IGF or somatomedins) which are themselves growth hormone dependent, inhibit ...
M. S. Sheppard, R. M. Bala
core   +1 more source

An investigation of endogenous ghrelin and growth hormone-releasing hormone following the consumption of two different relative doses of oral l-arginine [PDF]

, 2011
Individuals consume the amino acid L-arginine (L-arg) to obtain an anabolic response. However, little is known concerning the mechanism for using an oral dose.
McCarthy, Amanda Marie
core   +1 more source

Skeletal Growth Acceleration with Growth Hormone Secretagogues in Transgenic Growth Retarded Rats: Pattern‐Dependent Effects and Mechanisms of Desensitization

, 2001
The transgenic growth retarded (Tgr) rat is the first genetic model of growth hormone (GH) deficiency whose growth can be accelerated with exogenous GH secretagogues (GHSs). In this study, we have demonstrated that GHS-receptor (GHS-R) mRNA expression in
P. A. Houston, Houston, P. A., Wells, Timothy, T. Wells   +3 more
core   +1 more source

Favorable long-term effects of growth hormone replacement therapy on quality of life, bone metabolism, body composition and lipid levels in patients with adult-onset growth hormone deficiency

, 2011
Objective: The goal of growth hormone (GH) replacement is to improve quality of life (QoL) and prevent the long-term complications of GH deficiency (GHD).
Ueland, T., Schreiner, T., A.P. Jørgensen, K.J. Fougner, Fougner, K. J., Bollerslev, J., T. Schreiner, J. Bollerslev, Burman, Pia, Gudmundsen, O., P. Burman, Jorgensen, A. P., T. Ueland, O. Gudmundsen, Burman, Pia,, Lund University.   +15 more
core   +1 more source

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. [PDF]

Transl Androl Urol, 2020
Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI.   +7 more
europepmc   +1 more source

Effects of Combined Long-Term Treatment with a Growth Hormone-Releasing Hormone Analogue and a Growth Hormone Secretagogue in the Growth Hormone-Releasing Hormone Knock Out Mouse

, 2006
GH secretagogues (GHS) are synthetic ghrelin receptor agonists that stimulate GH secretion. It is not clear whether they act predominantly by stimulating the secretion of hypothalamic growth hormone-releasing hormone (GHRH), or directly on the ...
Schally, Andrew V, Fintini, Danilo, Salvatori, Roberto, Bowers, Cyril Y, Parlow, A.F, Alba, Maria   +5 more
core   +1 more source

The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone relase from acute rat hypothalamic explants.

, 1999
Growth hormone (GH) secretagogues (GH-releasing peptides and their non-peptide analogues) stimulate growth hormone release via specific G-protein coupled receptors both directly from the pituitary gland and through stimulation of the hypothalamus.
Tringalli G., COSTA, ALFREDO, Little J. A., Trainer P. J., Grossman A. B., Navarra P., Forsling M. L., Korbonits M.   +7 more
core  

Treatment of growth hormone deficiency in adults

, 2009
BACKGROUND: The Growth Hormone Research Society held a Consensus Workshop in Sydney, Australia, in March 2007 to review advances in the management of growth hormone (GH) deficiency in adults and to update consensus recommendations.
Johannsson, Gudmundur,
core   +1 more source

Activation of arcuate nucleus neurons by systemic administration of leptin and growth hormone-releasing peptide-6 in normal and fasted rats

, 1999
Both leptin and growth hormone secretagogues are believed to have stimulatory effects on the hypothalamic growth hormone pulse generator, though whether these are achieved through the same pathway is unknown. Systemic administration of a normally maximal
Luckman, Simon M.; id_orcid, Dickson, Suzanne L., Rosenzweig, Ivana   +2 more
core   +1 more source