Journal of Cachexia, Sarcopenia and MusclePlatinum‐based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects.
Ko‐Chieh Huang +3 more
doaj +1 more source
Growth hormone (GH) provocation tests and the response to GH treatment in GH deficiency [PDF]
, 2004 Objective: To identify factors, particularly the growth hormone (GH) provocation test result, affecting growth response to GH treatment in children with GH deficiency (GHD).Subjects: A total of 337 prepubertal GHD patients aged,10 years from the UK ...
Hindmarsh, PC, Dunger, DB, Cole, TJ
core
Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect [PDF]
, 2009 [Abstract] The first “growth hormone secretagogues” (GHSs) were discovered by Bowers et al. in 1977. In 1996 the GHSs receptor (GHS-R 1a) was cloned. The endogenous ligand for this receptor, ghrelin, was not identified until 1999.
Sangiao-Alvarellos, Susana +3 more
core +1 more source
, 2004 The action of a number of growth hormone secretagogues (GHS) on growth hormone (GH) secretion and gene expression was studied in a primary culture of pituitary cells isolated from the black seabream Acanthopagrus schlegeli.
Fung, C. K. +4 more
core +2 more sources
Growth Hormone Secretagogues as Potential Therapeutic Agents to Restore Growth Hormone Secretion in Older Subjects to Those Observed in Young Adults. [PDF]
J Gerontol A Biol Sci Med Sci, 2023 Smith RG, Thorner MO.
europepmc +1 more source
Osteosarcoma associated with diamond-blackfan anaemia: a case of a child receiving growth hormone therapy [PDF]
, 2004 Purpose: Diamond–Blackfan anaemia (DBA) is a rare pure congenital red cell aplasia, usually presenting in infancy or early childhood. The literature suggests a predisposition to haemopoietic malignancy but in addition solid tumours have been reported ...
Briggs, TW +4 more
core
RNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch) : an experimental model uncoupling the growth hormone and nutritional signals regulating growth [PDF]
, 2015 Background Coho salmon (Oncorhynchus kisutch) transgenic for growth hormone (Gh) express Gh in multiple tissues which results in increased appetite and continuous high growth with satiation feeding. Restricting Gh-transgenics to the same lower ration (TR)
Devlin, Robert +5 more
core +1 more source
, 2000 The proportion of elderly people is steadily growing in Western societies. The result is a disproportionate accumulation of the oldest and most vulnerable sector of the population, suffering from frailty-associated disorders and cardiovascular diseases ...
Bengtsson, B A +2 more
core
Growth hormone (GH)-independent stimulation of adiposity by GH secretagogues
, 2001 Growth hormone secretagogues (GHSs) stimulate growth hormone (GH) secretion, which is lipolytic. Here we compared the effects of twice daily s.c. treatment of GH and the GHS, ipamorelin, on body fat in GH-deficient (lit/lit) and in GH-intact (+/lit and +/
Ohlsson, Claes, +4 more
core +1 more source
Growth hormone increases dendritic spine density in primary hippocampal cell cultures
, 2020 Objective: Growth hormone (GH) is widely known for its peripheral effects during growth and development. However, numerous reports also suggest that GH exert pro-cognitive, restorative, and protective properties in the brain.
Zelleroth, Sofia, +5 more
core +1 more source