Growth hormone (GH) secretagogues (GH-releasing peptides and their non-peptide analogues) stimulate growth hormone release via specific G-protein coupled receptors both directly from the pituitary gland and through stimulation of the hypothalamus.
core +1 more source
Lean young‐onset diabetes in Bangladeshi adults showed marked estimated β‐cell dysfunction, high glycemic burden, modest insulin resistance, and dyslipidemia despite non‐obese BMI. These findings highlight the need for assessment beyond BMI‐based classification and individualised management.
Mashfiqul Hasan +8 more
wiley +1 more source
Platinum‐based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects.
Ko‐Chieh Huang +3 more
doaj +1 more source
Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system
Ghrelin, a newly discovered endogenous hormone that is produced by the stomach, and synthetic peptides have been identified recently as potent growth-hormone secretagogues.
Cao, Ji-Min, Chen, Chen, Ong, Huy
core +1 more source
Potential Applications for Growth Hormone Secretagogues Treatment of Amyotrophic Lateral Sclerosis. [PDF]
Meanti R +9 more
europepmc +1 more source
Management of growth hormone deficiency in adults
Growth hormone (GH) deficiency in adults is a recognised clinical entity. There is still, however, an ongoing debate of the clinical need and the importance of replacing GH in adults with severe GH deficiency.
Nilsson, Anna G, +2 more
core +1 more source
Rational Design, Discovery, and Synthesis of a Novel Series of Potent Growth Hormone Secretagogues⊥
In the joint experimental and computational efforts reported here to obtain novel chemical entities as growth hormone secretagogues (GHSs), a small database of peptides and non-peptides known to have GHS activity was used to generate and assess a 3D ...
Jun Nakano (1909162) +11 more
core +1 more source
Growth Hormone Secretagogues as Potential Therapeutic Agents to Restore Growth Hormone Secretion in Older Subjects to Those Observed in Young Adults. [PDF]
Smith RG, Thorner MO.
europepmc +1 more source
Could Overt Diabetes Be Triggered by Abuse of Selective Androgen Receptor Modulators and Growth Hormone Secretagogues? A Case Report and Review of the Literature. [PDF]
Sotorník R, Suissa R, Ardilouze JL.
europepmc +1 more source
Investigating the role of growth hormone receptor in oesophageal squamous-cell carcinoma. [PDF]
Includes abstract.Includes bibliographical references.Squamous-cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where incidence is high and survival is low.
Boris Krivochiev, Krivochiev, Boris
core +1 more source

