Results 261 to 270 of about 870,777 (309)
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Thyroid hormone and the growth plate
Reviews in Endocrine and Metabolic Disorders, 2006Thyroid hormone was first identified as a potent regulator of skeletal maturation at the growth plate more than forty years ago. Since that time, many in vitro and in vivo studies have confirmed that thyroid hormone regulates the critical transition between cell proliferation and terminal differentiation in the growth plate, specifically the maturation
Yvonne Y, Shao +2 more
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Physiology and pathophysiology of the growth plate
Birth Defects Research Part C: Embryo Today: Reviews, 2003AbstractLongitudinal growth of the skeleton is a result of endochondral ossification that occurs at the growth plate. Through a sequential process of cell proliferation, extracellular matrix synthesis, cellular hypertrophy, matrix mineralization, vascular invasion, and eventually apoptosis, the cartilage model is continually replaced by bone as length ...
R Tracy, Ballock, Regis J, O'Keefe
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Skeletal dysplasias and the growth plate
Clinical Genetics, 2007Skeletal dysplasias are disorders in which there is derangement in the growth or shape of the skeleton. Long bone grows from cartilage that persists near the ends until skeletal maturity as the growth plate. Developmental biology work has identified the major regulatory proteins in growth plate chondroyte function.
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The Normal and Abnormal Growth Plate
Radiologic Clinics of North America, 1987Skeletal growth is a dynamic process. A knowledge of the structure and function of the normal growth plate is essential in order to understand the pathophysiology of abnormal skeletal growth in various diseases. In this well-illustrated article, the authors provide a radiographic classification of abnormal growth plates and discuss mechanisms that lead
R, Kumar, J E, Madewell, L E, Swischuk
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Morphology and Biochemistry of the Growth Plate
Rheumatic Disease Clinics of North America, 1987The structure and function of the growth plate are discussed in detail by Dr. Brighton. Specifically, the blood supply, histology and histochemistry, biochemistry, and ultrastructure of the various zones of cartilagenous portion of the growth plate, as well as the bony and fibrous portions of the growth plate, are described.
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Scintigraphic evaluation of the growth plate
Seminars in Nuclear Medicine, 1993Multiphase bone scintigraphy is used to assess growth plate function in the growing skeleton. It can identify an evolving total or segmental closure by comparing an affected plate with a contralateral normal plate. Although visual interpretation is usually adequate, quantitative methods permit a more objective assessment.
H T, Harcke, G A, Mandell
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Newest Knowledge of the Growth Plate
Clinical Orthopaedics and Related Research, 1990Recent research, both clinical and basic science, has improved our understanding of the growth plate. New technological advances in surgical technique, tissue preparation, light and electron microscopy, tissue culture, immunology, and imaging allow a better appreciation of this complex function of growing bone.
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Characterization of growth plate mitochondria
Journal of Orthopaedic Research, 1984AbstractThe growth plate chondrocyte plays a central role in growth plate function. The purpose of this study was to characterize the respiratory and calcium transport properties of isolated mammalian growth plate chondrocytes and mitochondria obtained from these cells and to quantitate the mitochondrial weight and volume fraction in each zone of the ...
J L, Stambough +3 more
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The Growth Plate and Its Affections
The Journal of Bone & Joint Surgery, 1966This discussion has presented a brief outline of the growth plate as an organ responsible for longitudinal growth of bone in which certain physiological functions can be recognized. An attempt has been made to correlate some of the known affections of the plate with alterations in physiological and biochemical processes, in an effort to present a more ...
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Veterinary Record, 1976
Local disorders of bone growth form an important group of the orthopaedic problems that occur in foals. The recognition of the condition presented is essential so that the appropriate corrective measures may be instituted, and an accurate prognostication made.
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Local disorders of bone growth form an important group of the orthopaedic problems that occur in foals. The recognition of the condition presented is essential so that the appropriate corrective measures may be instituted, and an accurate prognostication made.
openaire +2 more sources