Results 81 to 90 of about 2,687 (162)

GRPR-targeted gold nanoparticles as selective radiotherapy enhancers in glioblastoma

Physics in Medicine & Biology
Abstract Objective. Glioblastoma multiforme (GBM) is the most diagnosed primary brain tumor in adults and remains associated with a poor prognosis due to its aggressive nature. As tumor recurrence is often observed after standard radiation treatment, the use of gold nanoparticles (AuNPs) to improve radiotherapy ...
Ana Rita C Teixeira, Joana Antunes, Catarina I G Pinto, Maria Paula Cabral Campello, Pedro Santos, Célia M Gomes, Antero J Abrunhosa, Jorge M Sampaio, António Paulo, Francisco Alves, Filipa Mendes   +10 more
openaire   +2 more sources

GRPR Gene [PDF]

, 2020
openaire   +1 more source

Unnatural amino acid substitutions to improve in vivo stability and tumor uptake of 68Ga-labeled GRPR-targeted TacBOMB2 derivatives for cancer imaging with positron emission tomography

EJNMMI Radiopharmacy and Chemistry
Background Overexpressed in various solid tumors, gastrin-releasing peptide receptor (GRPR) is a promising cancer imaging marker and therapeutic target. Although antagonists are preferable for the development of GRPR-targeted radiopharmaceuticals due to ...
Lei Wang, Hsiou-Ting Kuo, Zhengxing Zhang, Chengcheng Zhang, Chao-Cheng Chen, Devon Chapple, Ryan Wilson, Nadine Colpo, François Bénard, Kuo-Shyan Lin   +9 more
doaj   +1 more source

Evaluation of gastrin-releasing peptide receptor, prostate-specific membrane antigen, and neurotensin receptor 1 as potential biomarkers for accurate prostate cancer stratified diagnosis

EJNMMI Research
Background Studies on single-target PET imaging of gastrin-releasing peptide receptor (GRPR), prostate-specific membrane antigen (PSMA), or neurotensin receptor 1(NTR1) have been reported.
Ling Xiao, Zhihui Fang, Yongxiang Tang, Yanyan Sun, Zehua Zhu, Jian Li, Ming Zhou, Nengan Yang, Kai Zheng, Shuo Hu   +9 more
doaj   +1 more source

GRPR Overexpression Positive [PDF]

, 2020
openaire   +1 more source

GRPR wt Allele [PDF]

, 2020
openaire   +1 more source

Theranostic Targeting of GRPR and PSMA in Prostate Cancer

, 2023
This thesis is based on five original articles that investigated the theranostics of prostate cancer by gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) targeting. GRPR and PSMA are two extensively evaluated prostate cancer cell markers due to their overexpression in the majority of prostate cancer samples ...
openaire   +1 more source

First-in-human radiation dosimetry of the GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in patients with prostate and breast cancer. [PDF]

EJNMMI Res
Bjäreback A, Estenberg U, Tzortzakakis A, Axelsson R, Li C, Altena R, Tran TA, Hindorf C.   +7 more
europepmc   +1 more source

Spinal and supraspinal mechanisms of chronic itch: from neuronal circuits to the neuro-immune-microbial axis. [PDF]

Front Med (Lausanne)
Gao S, Liu M, Qi Z, Li Y, Xue Y, Gao C.
europepmc   +1 more source

Abstract 2581: GRPR- a potential role in radio-sensitization

Journal of Biological Chemistry, 2023
Jycole Bush, Michelle Villarreral, Addanki Kumar   +2 more
openaire   +1 more source