Results 171 to 180 of about 18,138 (288)

Anti-Inflammation and Anti-Pyroptosis Activities of Mangiferin via Suppressing NF-κB/NLRP3/GSDMD Signaling Cascades [PDF]

, 2022
Min Feng, Shaoqiang Wei, Shidong Zhang, Ying Yang   +3 more
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Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway [PDF]

, 2023
Kangyu Wang, Zhiyin Tang, Shuai Liu, Yan Liu, Huiqing Zhang, Haocheng Zhan   +5 more
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Deletion of gasdermin D promotes granulocytic myeloid-derived suppressor cell differentiation by decreased release of mitochondrial DNA to promote tumor escape

Cancer Immunology, Immunotherapy
Gasdermin D (GSDMD), an effector molecule of cell pyroptosis, is known to be activated in various cells during inflammation. However, the patterns of GSDMD activation in immune regulatory cells such as myeloid-derived suppressor cells (MDSCs) remain ...
Min Gu, Weiwei Chen, Shizhen Ding, Zhijie Lin, Li Qian, Weiming Xiao, Xiaoqin Jia, Guotao Lu, Weijuan Gong   +8 more
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SS31 alleviates LPS-induced acute lung injury by inhibiting inflammatory responses through the S100A8/NLRP3/GSDMD signaling pathway [PDF]

Peiyao Luo, Quankuan Gu, Jianpeng Wang, Xianyong Li, Nana Li, Wei Yang, Xianglin Meng, Mingyan Zhao   +7 more
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A new personalized vaccine strategy based on inducing the pyroptosis of tumor cells in vivo by transgenic expression of a truncated GSDMD N-terminus

, 2022
Jinrong He, Peng Zheng, Yongjun Chen, Jialong Qi, Chao Ye, Duo Li, Ying Yang, Ying Yang, Qingwen Liu, Yongmao Hu, Xiao Zheng, Weiran Li, Liangqun Hua, Zhongqian Yang, Haoqian Chen, Weiwei Huang, Wenjia Sun, Xu Yang, Qiong Long, Hongmei Bai, Yanbing Ma   +20 more
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Exosomes from IH- Induced bEnd3 Cells Promote OSA Cognitive Impairment via miR-20a-5p/MFN2 Mediated Pyroptosis of HT22 Cells

Nature and Science of Sleep
Zhifeng Chen,1– 4 Yulin Shang,5 Yanru Ou,1– 4 Li Zhou,1– 4 Ting Liu,1– 4 Subo Gong,6 Xudong Xiang,7 Yating Peng,1– 4 Ruoyun Ouyang1– 4 1Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha ...
Chen Z, Shang Y, Ou Y, Zhou L, Liu T, Gong S, Xiang X, Peng Y, Ouyang R   +8 more
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Pyroptosis in Osteoarthritis: Molecular Mechanisms and Therapeutic Implications

Journal of Inflammation Research
Yeping Chen,1,* Daofu Zeng,1,* Guizheng Wei,1,* Zhidong Liao,1,2 Rongyuan Liang,1 Xiajie Huang,1,2 William W Lu,3 Yan Chen1,2 1Department of Bone and Joint Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi,
Chen Y, Zeng D, Wei G, Liao Z, Liang R, Huang X, Lu WW, Chen Y   +7 more
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POS-063 DISULFIRAM AMELIORATES ISCHEMIA/REPERFUSION-INDUCED ACUTE KIDNEY INJURY BY SUPPRESSING THE CASPASE-11-GSDMD PATHWAY

, 2022
Qian Cai, Zhaoxing Sun, Manchen Bao, Shiqi Guo, Haijiang Wu, Xianjun Yu   +5 more
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Corynebacterium pseudotuberculosis phospholipase D targets mitochondrial sphingomyelin and induces NLRP3-GSDMD axis-mediated pyroptosis in macrophages to promote infection [PDF]

Xiaolin Li, Hong Lv, Cheng-Han Wu, Hexian Li, Wenyi Yi, Xiaoxin Niu, Qiuyue Peng, Chi Meng, Yongfeng Yuan, Shangquan Tian, Zhiying Wang, Rendong Fang, Zuoyong Zhou   +12 more
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Effect of TLR4 on Pyroptosis of Tubular Cell in Diabetic Nephropathy by GSDMD-N Activation

, 2020
Shuguang Yuan, Youliang Wang, Xuejing Zhu, Zhong Qu, Zhen Li, Si Wen, Guochun Chen, Hong Liu, Lin Sun, Fuyou Liu   +9 more
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