Convergent death programs in chronic obstructive pulmonary disease: how pyroptotic and ferroptotic crosstalk reshapes therapeutic paradigms. [PDF]
Huang A, Liu S, Lan J.
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Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review). [PDF]
Mao J, Luo M, Ruan L, Zhang C.
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Prognostic value of serum gasdermin D in predicting major adverse cardiovascular events in patients with unstable angina: a prospective observational study. [PDF]
Wu L, Zhou Z, Yang X, Wu Q, Tan W.
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ANXA2 promotes NLRP3 inflammasome activation and neuronal pyroptosis after intracerebral hemorrhage. [PDF]
Wu Q +6 more
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Artificial intelligence-driven peptide blocks gasdermin pyroptosis and alleviates inflammation. [PDF]
Liu M, Zhou H, Wu M.
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Statins targeting mevalonate-geranylgeranyl diphosphate pathway inhibit proliferation in NK/T lymphoma by promoting pyroptosis. [PDF]
Wang Y +5 more
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Galangin alleviates cold stress-induced splenic injury in Danzhou chickens by inhibiting NLRP3 inflammasome-mediated pyroptosis. [PDF]
Tian X +6 more
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HDAC4-mediated deacetylation of GSDMD prevents pyroptosis by inhibiting GSDMD ubiquitination
2023Abstract Gasdermin D (GSDMD) functions as a key pyroptotic executor and induces cytokine secretion after cleavage by inflammatory caspases. However, less is known about the role of posttranslational modifications (PTMs) in GSDMD-mediated pyroptosis.
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