Results 121 to 130 of about 360,657 (334)

Exogenous Silicon Attenuates Cadmium-Induced Oxidative Stress in Brassica napus L. by Modulating AsA-GSH Pathway and Glyoxalase System

Frontiers in Plant Science, 2017
Cadmium (Cd) brings a devastating health hazard to human being as a serious consequence of agricultural and environmental contamination. We demonstrated the protective effect of silicon (Si) on cadmium (Cd)-stressed rapeseed (Brassica napus L. cv.
M. Hasanuzzaman, K. Nahar, T. I. Anee, M. Fujita   +3 more
semanticscholar   +1 more source

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

REAÇÕES TRANSFUSIONAIS: CARACTERIZAÇÃO DAS REAÇÕES TRANSFUSIONAIS ADVERSAS OCORRIDAS EM HOSPITAIS ATENDIDOS PELO GRUPO GSH EM TODO PAÍS

Hematology, Transfusion and Cell Therapy
Objetivo: Descrever as principais reações transfusionais imediatas e tardias ocorridas em hospitais atendidos pelo Grupo GSH no país. Material e métodos: O levantamento dos dados, foi realizado pelas informações obtidas do sistema informatizado do Grupo ...
RA Bento, KJD Olio, LPS Fontenele, DSF Costa, SP Menchão, GDRF Cazeca, TOSB Marchesi, JAD Santos   +7 more
doaj   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

ÍNDICE DE ALOIMUNIZAÇÃO ERITROCITÁRIA EM PACIENTES ATENDIDOS PELAS AGÊNCIAS TRANSFUSIONAIS DO GRUPO GSH NÍVEL NACIONAL

Hematology, Transfusion and Cell Therapy
Objetivo: Analisar a incidência de aloimunização em pacientes internados nos hospitais das agências transfusionais do país atendidas pela Grupo GSH. Material e métodos: Estudo retrospectivo realizado através do levantamento de dados obtidos do sistema ...
KJD Olio, RA Bento, LPS Fontenele, DSF Costa, SP Menchão, GDRF Cazeca, TOSB Marchesi, JAD Santos   +7 more
doaj   +1 more source

The effect of glutathione on human nuclear chromatin decondensation [PDF]

Introduction: During spermiogendsis, sperm chromatin histones are replaced by protamine. After fertilization, the sprem nucleus is decondenced by glutathione (GSH).
رضازاده ولوجردی, مجتبی, سقا, محسن, نصر اصفهاني, محمد حسين   +2 more
core  

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

PROPOSTA DE AJUSTE DO PROTOCOLO DE RESERVA CIRÚRGICA DE HEMOCOMPONENTES DE UM HOSPITAL COM BASE NA METODOLOGIA MSBOS

Hematology, Transfusion and Cell Therapy
Introdução: Frequentemente, como relatado em literatura e visto na prática, há um excesso de pedidos de reserva de hemocomponentes em cirurgias eletivas, o que extrapola as necessidades reais, gerando desnecessariamente sobrecarga nos serviços de banco ...
EAF Oliveira, MCM Campos, LPS Fontenele, FCV Perini, LFF Dalmazzo   +4 more
doaj   +1 more source

An inorganic prodrug, tellurium nanowires with enhanced ROS generation and GSH depletion for selective cancer therapy

Chemical Science, 2019
A kind of inorganic prodrug, tellurium nanowires with enhanced ROS generation and GSH depletion, was developed for selective cancer therapy with high efficacy.
Ying Wu, Tao Guo, Yuan Qiu, Yan Lin, Yunyan Yao, Weibin Lian, Lisen Lin, Jibin Song, Huanghao Yang   +8 more
semanticscholar   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source