Results 201 to 210 of about 360,657 (334)

Mitochondria and Aging: Redox Balance Modulation as a New Approach to the Development of Innovative Geroprotectors (Fundamental and Applied Aspects). [PDF]

Int J Mol Sci
Mironova E, Kvetnoy I, Balazovskaia S, Antonov V, Poyarkov S, Mazzoccoli G.   +5 more
europepmc   +1 more source

Immunomodulatory Fibrous Scaffold with Dual Enzyme‐Mimic Activities Prevents Postsurgical Tumor Recurrence

Advanced Science, EarlyView.
A MnOx nanozyme‐functionalized electrospun fibrous scaffold is developed for postoperative therapy by leveraging its intrinsic physicochemical and immunomodulatory properties. Integrating POD‐ and CAT‐like activities, the scaffold induces immunogenic cell death, alleviates hypoxia, and reverses immunosuppression, while simultaneously recruiting and ...
Xiaoyi Zhao, Zhuolong Jiao, Yue Wang, Huimeng Gu, Longfei Li, Jian Song, Chen Xu, Jiajia Xue, Fu‐Jian Xu, Nana Zhao   +9 more
wiley   +1 more source

Consequences of iron exposure and glutathione depletion on redox balance, lipidome, and neurotransmission in C. elegans. [PDF]

Redox Biol
Gremme A, Gerisch E, Wieland D, Hillebrand J, Drews F, Pirritano M, Weishaupt AK, Fuss J, Schwantes V, Scholz J, Michaelis V, Thiel A, McColl G, Michalke B, Simon M, Hayen H, Bornhorst J.   +16 more
europepmc   +1 more source

Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience

Advanced Science, EarlyView.
Atomically precise clusterzymes, engineered via atomic and ligand design, serve as programmable platforms for neuroscience applications. They demonstrate tailored biocatalysis for neuroinflammation, tunable optical properties for deep‐tissue bioimaging and 3D visualization, and enhanced charge transfer for brain–computer interfaces.
Si Sun, Di Liu, Sufei Zhou, Yang Wang, Hao Wang, Ziliang Zheng, Xiao‐Dong Zhang   +6 more
wiley   +1 more source

A dual-responsive NIR fluorescent probe for GSH and viscosity: applications in models of cellular inflammation and apoptosis. [PDF]

RSC Adv
Li S, Xing W, Wen W, Yan M, Ren H.
europepmc   +1 more source

Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.

Angewandte Chemie, 2017
C. Yin, K. Xiong, Fangjun Huo, James C. Salamanca, R. Strongin   +4 more
semanticscholar   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Redox metabolism in cell senescence: focusing on contributions from the metabolomic field. [PDF]

Front Mol Biosci
Chacón E, Grünwaldt G, Marmisolle I, Martínez J, Quijano C.   +4 more
europepmc   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Sleep Disorders in Climacteric Women: Glutathione, Glutathione S-Transferase P1 and Gut Microbiome Interrelation. [PDF]

Pathophysiology
Semenova N, Garashchenko N, Nikitina O, Kolesnikov S, Belkova N, Klimenko E, Smurova N, Novikova E, Madaeva I, Kolesnikova L.   +9 more
europepmc   +1 more source