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Sex-Related Differences in Physiological and Biochemical Responses of <i>Populus nigra</i> to Bifunctionalized Silver Nanoparticles and Silver Ions Exposure In Vitro. [PDF]

Plants (Basel)
Iori V, Gentile D, Casentini B, Camoni L, Fiorillo A, Kuzminsky E, Venditti I, Iannelli MA.   +7 more
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Nanosensors Monitor Intracellular GSH Depletion: GSH Triggers Cu(II) for Tumor Imaging and Inhibition

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AbstractGlutathione (GSH) is the primary antioxidant in cells, and GSH consumption will break the redox balance in cells. Based on this, a method that uses high concentrations of GSH in the tumor microenvironment to trigger the redox reaction of Cu(II) to generate copper nanoprobes with fluorescence and tumor growth inhibition properties is proposed ...
Yihan Wang, Ke Huang, Tingya Wang, Liu Liu, Fangfang Yu, Wenyu Sun, Wenyan Yao, Hongjie Xiong, Xiaohui Liu, Hui Jiang, Xuemei Wang   +10 more
openaire   +3 more sources

Imbalanced GSH/ROS and sequential cell death

Journal of biochemical and molecular toxicology, 2021
Reactive oxygen species (ROS) are produced in cells during metabolic processes. Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA, proteins, and small biomolecules, that is, glutathione (GSH) and unsaturated fatty acids. GSH
Ting Liu, Li Sun, Yubin Zhang, Yonglin Wang, Jiang Zheng   +4 more
semanticscholar   +1 more source

Exogenous glutathione alleviates chilling injury in postharvest bell pepper by modulating the ascorbate-glutathione (AsA-GSH) cycle.

Food Chemistry, 2021
We investigated the effect of exogenous glutathione (GSH) on chilling injury (CI) in postharvest bell pepper fruits stored at low temperature and explored the mechanism of this treatment from the perspective of the ascorbate-glutathione (AsA-GSH) cycle ...
Miao-miao Yao, Wanying Ge, Qian Zhou, Xin Zhou, Man-li Luo, Ying-bo Zhao, B. Wei, Shu-juan Ji   +7 more
semanticscholar   +1 more source

2D Piezoelectric Bi2MoO6 Nanoribbons for GSH‐Enhanced Sonodynamic Therapy

Advances in Materials, 2021
Reducing the scavenging capacity of reactive oxygen species (ROS) and elevating ROS production are two primary goals of developing novel sonosensitizers for sonodynamic therapy (SDT). Hence, ultrathin 2D Bi2MoO6–poly(ethylene glycol) nanoribbons (BMO NRs)
Yushan Dong, Shuming Dong, Bin Liu, Chen Yu, Jing Liu, Dan Yang, Piaoping Yang, Jun Lin   +7 more
semanticscholar   +1 more source

Multifunctional nanolocks with GSH as the key for synergistic ferroptosis and anti-chemotherapeutic resistance.

Biomaterials, 2022
The emergence of chemotherapeutic resistance, which is closely related to the oxidative stress defense induced by the imbalance of reactive oxygen species (ROS), is one of the important reasons for the failure of anti-tumor therapy.
Jiawei Zhu, Xiaorui Wang, Yan Su, Jinjun Shao, Xuejiao Song, Wenjun Wang, Liping Zhong, Lu Gan, Yongxiang Zhao, Xiaochen Dong   +9 more
semanticscholar   +1 more source

GSH-Responsive Nanoprodrug to Inhibit Glycolysis and Alleviate Immunosuppression for Cancer Therapy.

Nano letters (Print), 2021
Blocking energy metabolism of cancer cells and simultaneously stimulating the immune system to perform immune attack are significant for cancer treatment. However, how to potently deliver different drugs with these functions remains a challenge.
Xiaohan Liu, Yanhua Li, Kaiye Wang, Yuanyuan Chen, M. Shi, Xia Zhang, W. Pan, Na Li, B. Tang   +8 more
semanticscholar   +1 more source

H2O2 Self-Supplying and GSH-Depleting Nanoplatform for Chemodynamic Therapy Synergetic Photothermal/Chemotherapy.

ACS Applied Materials and Interfaces, 2021
Chemodynamic therapy (CDT) that utilizes Fenton-type reactions to convert endogenous hydrogen peroxide (H2O2) into hydroxyl radicals (•OH) is a promising strategy in anticancer treatment, but the overexpression of glutathione (GSH) and limited endogenous
Zhimei Xiao, Wenbao Zuo, Luping Chen, Liang Wu, Nian Liu, Jinxue Liu, Quanyi Jin, Yilin Zhao, Xuan Zhu   +8 more
semanticscholar   +1 more source

GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy

Advances in Materials, 2020
Nanocatalytic therapy, using artificial nanoscale enzyme mimics (nanozymes), is an emerging technology for therapeutic treatment of various malignant tumors. However, the relatively deficient catalytic activity of nanozymes in the tumor microenvironment (
Shuming Dong, Yushan Dong, Tao Jia, Shikai Liu, Jing Liu, Dan Yang, Fei He, S. Gai, Piaoping Yang, Jun Lin   +9 more
semanticscholar   +1 more source