Results 151 to 160 of about 35,497 (235)

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu, Prince Asare, Michelle Yeboah‐Manu, Stephen Osei‐Wusu, Emelia Danso Konadu, Adwoa Asante‐Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S. Afriyie‐Mensah, Dorothy Yeboah‐Manu, Yacoba Atiase   +11 more
wiley   +1 more source

Protective effects of paeonol on cardiovascular complications in diabetes mellitus involves modulation of PI3K /Akt-GSK-3β signalling, regulation of protease-activated receptor-1 expressions and down-regulation of inflammatory mediators

, 2015
Jun Li, Zeqing Xu, Ling Ling Bao, Zhi‐Cao Li, Jiaxiang Qu   +4 more
openalex   +2 more sources

Telmisartan protects central neurons against nutrient deprivation-induced apoptosis in vitro through activation of PPARγ and the Akt/GSK-3β pathway [PDF]

, 2014
Tao Pang, Lixin Sun, Tao Wang, Zhenzhou Jiang, Hong Liao, Luyong Zhang   +5 more
openalex   +1 more source

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon, James McStravick, Libby Henthorn, Stephen J. Bawden, Jonathan C. Y. Tang, Rachel Dunn, Ryosuke Makino, Kenneth Smith, Javier T. Gonzalez, Nathan Hodson, James P. Morton, Aneurin J. Kennerley, Mark A. Hearris   +12 more
wiley   +1 more source

TMEM88 modulates the proliferation and metastasis of HCC via the GSK-3β/β-catenin pathway. [PDF]

BMC Cancer
Zhang J, Chen X, Li W, Chen Y, Peng L, Liao H, Xuyun X, Chen T, Chen J.   +8 more
europepmc   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

The Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier, Dobromir Dobrev, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Machine learning guided virtual screening of FDA approved drugs targeting GSK-3β in Alzheimer's disease. [PDF]

Sci Rep
Kumar BS, Dinesh BGH, Ganjipete S, Ramar M, Ammunje DN, Kunjiappan S, Chidambaram K, Pavadai P.   +7 more
europepmc   +1 more source

Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus

, 2015
Cristóforo Scavone
openalex  

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

MaR1 and NGF combine to inhibit autophagy through the GSK-3β/β-catenin pathway to promote sciatic nerve repair. [PDF]

J Transl Med
Zhang Y, Zhao S, Wu S, Niu H, Gu L, Song Y.   +5 more
europepmc   +1 more source