Results 161 to 170 of about 33,158 (224)

Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response

open access: yesTransfusion, EarlyView.
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn   +14 more
wiley   +1 more source

Co‐ingesting whey protein with dual‐source carbohydrate enhances amino acid availability without compromising post‐exercise liver glycogen resynthesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Graphical overview of the experimental study. The upper‐left panel presents the research question, and the bottom‐left panel provides a schematic overview of the experimental design. The right‐hand panel depicts repetitive spectral data obtained by magnetic resonance spectroscopy, liver glycogen content during the 5 h post ...
Sophie C. Hannon   +12 more
wiley   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera   +6 more
wiley   +1 more source

ApoE4 Upregulates GSK-3β to Aggravate Alzheimer-Like Pathologies and Cognitive Impairment in Type 2 Diabetic Mice. [PDF]

open access: yesCNS Neurosci Ther
Wang Y   +11 more
europepmc   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K   +5 more
wiley   +1 more source

Accumulation of GSK-3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission. [PDF]

open access: yesAging Cell
Liu F   +11 more
europepmc   +1 more source

WWOX Mutation as a Rare Cause of Neonatal‐Infantile Parkinsonism Mimicking a Neurotransmitter Disorder: A Case Report

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Ozge Serce Pehlevan   +3 more
wiley   +1 more source

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