Results 171 to 180 of about 35,497 (235)
Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors. [PDF]
Marotta G +15 more
europepmc +1 more source
The Role of Akt-GSK-3β Signaling and Synaptic Strength in Phencyclidine-Induced Neurodegeneration [PDF]
Gang Lei, Yan Xia, Kenneth M. Johnson
openalex +1 more source
ABSTRACT Background Co‐existence of multiple cardiovascular‐kidney‐metabolic (CKM) conditions, such as chronic kidney disease (CKD), type 2 diabetes (T2D), and cardiovascular disease, is common. The interconnected nature of CKM conditions emphasizes the need for an interprofessional approach to patient care.
Wendy L. St. Peter +12 more
wiley +1 more source
MARCH5 Promotes Cardiac Hypertrophy by Regulating Akt/mTOR/Gsk-3β/GATA4 Signalling Pathway. [PDF]
Li G, Wu F, Lei F, Zhang J, Liao Y.
europepmc +1 more source
GSK-3β Disrupts Neuronal Oscillatory Function to Inhibit Learning and Memory in Male Rats
Abdalla M. Albeely +2 more
openalex +2 more sources
ABSTRACT Background Cancer cachexia is a complex syndrome marked by weight loss and muscle wasting, significantly impacting patient quality of life and survival. Mechanistically, it is characterized by suppressed protein synthesis and enhanced muscle catabolism, with the role of endoplasmic reticulum (ER) stress and unfolded protein response (UPR ...
Yusaku Kaneko +6 more
wiley +1 more source
ApoE4 Upregulates GSK-3β to Aggravate Alzheimer-Like Pathologies and Cognitive Impairment in Type 2 Diabetic Mice. [PDF]
Wang Y +11 more
europepmc +1 more source
Mitochondrial Adaptations in Skeletal Muscle Following Incretin‐Based Therapies: In Vitro
ABSTRACT Background Incretin‐based therapies such as glucagon‐like peptide‐1 receptor agonists (GLP‐1Ras), dual GLP‐1/GIP agonists and amylin analogues have demonstrated significant weight loss benefits. However, their impact on skeletal muscle mitochondrial function, particularly under metabolic stress, remains unclear. This study aimed to investigate
Victoria Old +6 more
wiley +1 more source

