Results 171 to 180 of about 35,497 (235)

Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors. [PDF]

open access: yesJ Med Chem
Marotta G   +15 more
europepmc   +1 more source

Retraction for Piracha et al., “Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway”

open access: diamond
Zahra Zahid Piracha   +8 more
openalex   +1 more source

A Scoping Review of Pharmacist‐Based Interprofessional Interventions for Management of Cardiovascular‐Kidney‐Metabolic Conditions

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 4, April 2026.
ABSTRACT Background Co‐existence of multiple cardiovascular‐kidney‐metabolic (CKM) conditions, such as chronic kidney disease (CKD), type 2 diabetes (T2D), and cardiovascular disease, is common. The interconnected nature of CKM conditions emphasizes the need for an interprofessional approach to patient care.
Wendy L. St. Peter   +12 more
wiley   +1 more source

Inhibition of N‐Terminal Acetyltransferase C Mitigates Endoplasmic Reticulum Stress–Mediated Muscle Atrophy in Cancer Cachexia

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cancer cachexia is a complex syndrome marked by weight loss and muscle wasting, significantly impacting patient quality of life and survival. Mechanistically, it is characterized by suppressed protein synthesis and enhanced muscle catabolism, with the role of endoplasmic reticulum (ER) stress and unfolded protein response (UPR ...
Yusaku Kaneko   +6 more
wiley   +1 more source

ApoE4 Upregulates GSK-3β to Aggravate Alzheimer-Like Pathologies and Cognitive Impairment in Type 2 Diabetic Mice. [PDF]

open access: yesCNS Neurosci Ther
Wang Y   +11 more
europepmc   +1 more source

Mitochondrial Adaptations in Skeletal Muscle Following Incretin‐Based Therapies: In Vitro

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Incretin‐based therapies such as glucagon‐like peptide‐1 receptor agonists (GLP‐1Ras), dual GLP‐1/GIP agonists and amylin analogues have demonstrated significant weight loss benefits. However, their impact on skeletal muscle mitochondrial function, particularly under metabolic stress, remains unclear. This study aimed to investigate
Victoria Old   +6 more
wiley   +1 more source

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