Results 181 to 190 of about 35,497 (235)

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Potential therapeutic GSK-3β inhibitor 9-ING-41 is active in combination with venetoclax in double-hit lymphoma (DHL). [PDF]

Cancer Biol Ther
Lei H, Zhang Y, Zheng H, Shi P, Wei X, Guo X.   +5 more
europepmc   +1 more source

Network Pharmacology Combined With Clinical Retrospective Analysis to Investigate the Potential Mechanisms and Clinical Significance of Folate in Treating Spinal Cord Injury

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Folate is an indispensable nutrient involved in key biological processes, including enzymatic reactions, DNA replication, metabolic regulation, and methylation. Studies indicate that folate promotes neuronal regeneration and repair in patients with spinal cord injury (SCI); however, its precise mechanisms remain unclear.
Xiaolei Chu, Jiajia Liang, Jiaojiao Sun, Wenjie Liu, Lei Zhang, Zheng Xing, Qingwen Li, Qi Li   +7 more
wiley   +1 more source

Behavioral benefits of GSK-3β inhibition and state-dependent microtubule signatures in the <i>Fmr1</i>-KO mouse. [PDF]

Front Neurosci
Kealy J, Callaghan C, Freeburn A, Thornton A, Greene C, Garrone B, Milanese C, Bianchi M.   +7 more
europepmc   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Favorable Eruption Despite External Replacement Root Resorption in Delayed Replantation of Avulsed Teeth Treated With Regenerative Endodontics—An Observational Study

Dental Traumatology, Volume 42, Issue 2, Page 160-175, April 2026.
ABSTRACT Aim To assess the eruption patterns and progression of external replacement root resorption of eight teeth that were avulsed and had delayed replantation treated by regenerative endodontic treatment (RET). Methodology In total, 102 traumatised anterior teeth were treated with regenerative endodontic treatment (RET) between December 2016 and ...
Arieh Y. Kaufman, Margarita Yoshpe, Shmuel Einy, Bill Kahler   +3 more
wiley   +1 more source

Accumulation of GSK-3β in Interneurons Impairs Adult Hippocampal Neurogenesis by Inhibiting GABAergic Transmission. [PDF]

Aging Cell
Liu F, Cui JJ, Li XL, Zhang ZM, Liang SH, Sun Y, Li JM, Qu HL, Ye J, Guo QP, Zheng Q, Liu YF.   +11 more
europepmc   +1 more source

Inhibition of TPA‑induced metastatic potential by morin hydrate in MCF‑7 human breast cancer cells via the Akt/GSK‑3β/c‑Fos signaling pathway

, 2020
Kyu‐Shik Lee, Gi Suk Nam, Junyoung Baek, Soyoung Kim, Kyung‐Soo Nam   +4 more
openalex   +2 more sources

Molecular Markers Distinguishing Early‐Stage Mycosis Fungoides From Atopic Dermatitis Skin Lesions

Experimental Dermatology, Volume 35, Issue 4, April 2026.
ABSTRACT Mycosis fungoides (MF) is the most common type of primary cutaneous T‐cell lymphoma, a disease characterized by malignant T cells that home to the skin. In early stages, clinical presentation is often indistinguishable from benign chronic inflammatory skin diseases such as atopic dermatitis (AD), posing a challenge for proper diagnosis and ...
Brandon D. Ng, Conor Whelan, Natalia Alkon, Agata Kurowski, Constanze Jonak, Patrick M. Brunner   +5 more
wiley   +1 more source

AZD1080, a specific inhibitor of GSK‑3β, inhibits stemness and malignancies in osteosarcoma cancer stem‑like cells. [PDF]

Mol Med Rep
Guo P, Lou Z, Gong H, Hou X, Zhang C, Wang B, Du K.   +6 more
europepmc   +1 more source