Results 141 to 150 of about 5,937 (164)

Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1997
Differences in human cancer susceptibility have been attributed to polymorphisms of carcinogen metabolizing enzymes. Our efforts have focused on the systems responsible for metabolism of aromatic and heterocyclic amines found in cigarette smoke and in cooked foods. Cytochrome P4501A2 (CYP1A2), which catalyzes aromatic and heterocyclic amine N-oxidation,
S, MacLeod, R, Sinha, F F, Kadlubar, N P, Lang   +3 more
openaire   +2 more sources

The impact of GSTM1/GSTT1 polymorphism for the risk of oral cancer

Clinical Oral Investigations, 2015
Since development of oral squamous cell cancer (OSCC) is triggered by various noxa, different variants of the antioxidant glutathione S-transferases (GSTs) can counteract toxic compounds (e.g., tobacco smoke). Because different polymorphisms of GST are known to have an increased sensitivity to carcinogenic agents, the aim of this study was to analyze ...
Maximilian, Krüger, Andreas Max, Pabst, Benjamin, Mahmoodi, Burkhard, Becker, Peer Wolfgang, Kämmerer, Felix Peter, Koch   +5 more
openaire   +2 more sources

Glutathione S-Transferases GSTM1 and GSTT1 Polymorphisms and Asbestosis

Journal of Occupational & Environmental Medicine, 2007
In a nested case-control study, the authors investigated whether the deletion polymorphism of glutathione S-transferases GSTM1 and GSTT1 represents a risk factor for the development of asbestosis.In total, 262 cases with asbestosis and 265 controls, selected from a cohort of 2080 workers occupationally exposed to asbestos, were genotyped for GSTM1 and ...
Alenka, Franko, Metoda, Dodic-Fikfak, Niko, Arnerić, Vita, Dolzan   +3 more
openaire   +2 more sources

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2014
The study was aimed to assess the prevalence of GSTM1 gene polimrophism in the patients with the external genital endometriosis. There was demonstrated at the random sample that the frequency of deletion polymorphism of GSTM1 is corresponding to the average rate furthermore the severity of clinical course and the response to the standard treatment was ...
openaire   +1 more source

NAT2 and GSTM1 DNA polymorphisms: increased GSTM1 (active) genotypes in endometriosis

Fertility and Sterility, 2002
F.Z. Bischoff, D. Marquez-Do, D. Dang, S.A. Carson, J.E. Buster, J.L. Simpson   +5 more
openaire   +1 more source

Polymorphism at the glutathione S-transferase GSTM1 locus: A study of the frequencies of the GSTM1 A, B, A/B and null phenotypes in Nigerians

Clinica Chimica Acta, 1994
Zhao, L, Alldersea, J, Fryer, A, Tighe, A, Ollier, William, Thomson, W, Jones, P, Strange, R. C.   +7 more
openaire   +3 more sources

Glutathione S-Transferase GSTM1 Phenotypes and Protection Against Cutaneous Tumours

Lancet, The, 1994
Anthony A Fryer, Julie Alldersea, B Bowers   +2 more
exaly  

NAT2 Slow Acetylation, GSTM1 Null Genotype, and Risk of Bladder Cancer: Results From the Spanish Bladder Cancer Study and Meta-Analyses

Lancet, The, 2005
Adonina Tardón, Alfredo Carrato, Consol Serra   +2 more
exaly  

The GSTM1 and GSTT1 Null Genotypes Increase the Risk for Type 2 Diabetes Mellitus and the Subsequent Development of Diabetic Complications: A Meta-Analysis

Current Diabetes Reviews, 2017
Yashmin Choudhury, Sankar Kumar Ghosh, Aditi Bhowmik   +2 more
exaly  

Null Genotypes of GSTM1 and GSTT1 Contribute to Male Factor Infertility Risk: A Meta-Analysis

Fertility and Sterility, 2013
Jian-Ping Liu
exaly