Results 121 to 130 of about 5,937 (164)

Lack of association between the glutathione-s-transferase genes (GSTT1 and GSTM1) and nasal polyposis

, 2006
Objectives: To evaluate the glutation-S-transferase (GST) polymorphisms (GSTM1 and GSTT1) in nasal polyposis (NP). Methods: The study population consisted of 102 unrelated healthy individuals and 98 patients with NP (67 without asthma, 31 with asthma ...
Öztürk, Kayhan, Çora, Tülin, Arbağ, Hamdi, Sarı, Fatih, Ulusoy, Bülent, Acar, Hasan   +5 more
core  

Is the GSTM1 Null Polymorphism a Risk Factor for Primary Angle-Closure Glaucoma among Iranian Population?

Acta Medica Iranica, 2015
Glutathione S-transferases (GSTs) are members of multigenic family which have the essential functionin cells as an antioxidant. In the present study we studied the polymorphism of GSTT1 and GSTM1 deletion genotypes in Iranian patients with primary closed
Fatemeh Kazemi Safa, Gholamreza Shahsavari, Arezou Miraftabi   +2 more
doaj  

Estudio de las deleciones de los genes GSTM1 y GSTT1 y del polimorfismo Ile105Val del gen GSTP1 en pacientes con enfermedad ósea de Paget

, 2014
Fundamento: La enfermedad ósea de Paget (EOP) es un trastorno focal del hueso con aumento el número, tamaño y actividad de los osteoclastos. Algunos datos epidemiológicos apoyan la teoría de su relación con agentes ambientales tóxicos o infecciosos.
Montilla Morales C, Corral E, Sánchez-González MD, Mirón-Canelo JA, Alonso M, González-Sarmiento R, Pérez-Garrido L, Calero-Paniagua I, Usategui-Martín R, Carranco-Medina TE, Pino-Montes J, Quesada-Moreno A, Hidalgo-Calleja C   +12 more
core  

No contribution of GSTM1 and GSTT1 null genotypes to the risk of neutropenia due to benzene exposure in Southeastern Brazil

, 2017
Exposure to benzene has been associated with haematological diseases such as neutropenia (NEB) and acute myeloid leukaemia (AML). We tested whether the null genotypes of the GSTM1 and GSTT1 genes, involved in benzene inactivation, altered the risk for ...
Lorand-Metze, Irene, Nascimento, Helvia, Saad, Sara Terezinha Olalla, Costa, Fernando Ferreira, Lourenco, Gustavo Jacob, Lima, Carmen Silvia Passos   +5 more
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CYP2D6 And GSTM1 Genotypes in a Polish Population

European Journal of Clinical Pharmacology, 1999
The aim of the present study was to investigate the distribution of the CYP2D6 and GSTM1 genotypes in a Polish population.One hundred and forty-five unrelated healthy individuals from the western region of Poland were studied. The CYP2D6 genotype was analysed by means of polymerase chain reaction (PCR) amplification for the CYP2D6*3 and CYP2D6*4 ...
Andrzej Pawlik, Barbara Gawronska-Szklarz   +1 more
exaly   +4 more sources

GSTM1 Polymorphism and Oral Squamous Cell Carcinoma

Oral Oncology, 2004
We investigated the frequency of the GSTM1 genotypes in 70 Brazilian patients with oral squamous cell carcinoma (OSCC) and 82 age-sex matched controls. The GSTM1 genotypes were studied by PCR-based methods. The frequency of male patients with OSCC and null for the GSTM1 (70.5%) was statistically different from the male patients from the control group ...
Ricardo S Gomez, Luiz De Marco
exaly   +3 more sources

CYP1A1, CYP19, And GSTM1 Polymorphisms Increase the Risk of Endometriosis

Fertility and Sterility, 2003
To investigate the possibility of genetic contribution of CYP1A1, CYP19, GSTM1, and GSTT1 polymorphisms to endometriosis.Genetic polymorphism analysis.Case-control study.A group of 275 women with sporadic endometriosis was compared with a group of 346 fertile, endometriosis-free women.Surgical, laparoscopic, and histological examination.Blood specimens
Dimitrios A. Arvanitis, Ioannis Matalliotakis, Georgios E Koumantakis   +2 more
exaly   +3 more sources

Expression of GSTM1 in angiofibromas

The Journal of Laryngology & Otology, 2002
The aetiology of juvenile nasopharyngeal angiofibroma (JNA) is largely unknown. In this study, we have investigated the expression of glutathione S transferase M1 (GSTM1) gene in angiofibroma. The GSTM1 allele gene locus is normally found in all human beings.
K, Gautham, S B, Ogale, R U, Shraddha, D, Ajay   +3 more
openaire   +2 more sources

A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer

The FASEB Journal, 2009
ABSTRACT Although a number of studies have been conducted to address the relation between a gene deletion polymorphism of glutathione S‐transferase M1 (GSTM1) and breast cancer, no definite conclusion has been reached and no clear ...
Ke-Da, Yu, Gen-Hong, Di, Lei, Fan, Jiong, Wu, Zhen, Hu, Zhen-Zhou, Shen, Wei, Huang, Zhi-Ming, Shao   +7 more
openaire   +2 more sources

GSTM1, GSTT1, and NQO1 polymorphisms in cervical carcinogenesis

Human Cell, 2015
The aim of the study is to investigate the clinical significance of glutathione-S-transferase GSTM1, GSTT1, and NQO1 c.609C>T (rs1800566) genetic polymorphisms in cervical carcinogenesis. GSTM1, GSTT1, and NQO1 polymorphisms together with human papillomavirus (HPV) types were examined in a total of 192 cervical smear in exfoliated cervical cell samples
Osamu, Nunobiki, Masatsugu, Ueda, Hikari, Akise, Shinji, Izuma, Kiyo, Torii, Yoshiaki, Okamoto, Ichiro, Tanaka, Sadamu, Noda, Kyoko, Akashi, Taro, Higashida   +9 more
openaire   +2 more sources