Results 101 to 110 of about 5,937 (164)

Tissue-specific variability in protein expression of cytochrome P450 and glutathione S-transferase isoenzymes in non-small cell lung carcinoma

Arhiv za Higijenu Rada i Toksikologiju
Earlier tissue-based studies report heterogeneous CYP and GST protein expression in non-small cell lung cancer (NSCLC), but simultaneous assessment of phase I and II enzymes in paired tumour and peripheral normal tissues remains limited and their ...
Kılıç Murat, Oğuztüzün Serpil, Çelik Sezgin, Demirağ Funda, Bıçakçıoğlu Pınar, İşcan Mümtaz, Ada Ahmet Oğuz   +6 more
doaj   +1 more source

Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer

Yonsei Medical Journal, 2007
Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral cancer is tobacco use, we hypothesized that polymorphic genes coding for tobacco carcinogen-metabolizing enzymes may play a role in oral cancer susceptibility.To investigate the association between ...
Cha, In-Ho, Park, Jong Yun, Chung, Won-Yoon, Choi, Min-Ah, Kim, Hyung-Jun, Park, Kwang-Kyun   +5 more
openaire   +3 more sources

Effects of GSTM1 in rheumatoid arthritis; results from the Swedish EIRA study.

PLoS ONE, 2011
ObjectiveGlutathione-S-transferases (GSTs) play an important role in tobacco smoke detoxification, interestingly approximately 50% of individuals in most human populations lack the gene GSTM1 due to copy number variation (CNV).
Emeli Lundström, Toinette Hartshorne, Kelly Li, Staffan Lindblad, Marius C Wick, Camilla Bengtsson, Lars Alfredsson, Lars Klareskog, Leonid Padyukov   +8 more
doaj   +1 more source

GSTT1 and GSTM1 genotypes in cases and controls.

, 2014
GSTT1 and GSTM1 genotypes in cases and controls.
Chen Shen (415899), Wei-wei Jiao (2198146), An-xia Jiao (677097), Qing-qin Yin (431854), Wei Zhao (14321), A-dong Shen (431857), Jing Xiao (356412), Dan Shen (380488), Jian-ling Tian (535862), Evelyne Jacqz-Aigrain (362302), Xi-rong Wu (5655628), Lin Sun (105539), Fang Liu (13271), Hui Qi (460415)   +13 more
core   +1 more source

Association of GSTP1, GSTT1 and GSTM1 Gene Variants with Coronary Artery Disease in Iranian Population: A Case–Control Study

International Journal of General Medicine, 2020
Alemeh Pourkeramati,1 Ehsan Zare Mehrjardi,1 Masoud Dehghan Tezerjani,2 Seyed Morteza Seifati1 1Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran; 2Abortion Research Centre, Yazd Reproductive Sciences ...
Pourkeramati A, Zare Mehrjardi E, Dehghan Tezerjani M, Seifati SM   +3 more
doaj  

RETRACTED: Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma.

PLoS ONE, 2016
The aim of this study was to evaluate specific glutathione S-transferase (GST) gene variants as determinants of risk in patients with clear cell renal cell carcinoma (cRCC), independently or simultaneously with established RCC risk factors, as well as to
Vesna M Coric, Tatjana P Simic, Tatjana D Pekmezovic, Gordana M Basta-Jovanovic, Ana R Savic Radojevic, Sanja M Radojevic-Skodric, Marija G Matic, Dejan P Dragicevic, Tanja M Radic, Ljiljana M Bogdanovic, Zoran M Dzamic, Marija S Pljesa-Ercegovac   +11 more
doaj   +1 more source

GSTM1 null genotype underpins recurrence of NF2 meningiomas

Frontiers in Oncology
IntroductionMeningiomas are the most common primary central nervous system (CNS) tumor in adults, comprising one-third of all primary adult CNS tumors. Although several recent publications have identified molecular alterations in meningioma including characteristic mutations, copy number alterations, and gene expression signatures, our understanding of
Anthony C. Johnson, Anthony C. Johnson, Erdyni N. Tsitsikov, Khanh P. Phan, Jeffrey A. Zuccato, Andrew M. Bauer, Christopher S. Graffeo, Sanaa Hameed, Tressie M. Stephens, Yufeng Liu, Gavin P. Dunn, Alla V. Tsytsykova, Pamela S. Jones, Ian F. Dunn   +13 more
openaire   +3 more sources

Meta-analysis of GSTM1 null genotype associated with HCC.

, 2012
Meta-analysis of GSTM1 null genotype associated with HCC.
Jiayong Yi (119067), Kang Song (119065), Yu Cai (112178), Xizhong Shen (119070)   +3 more
core   +1 more source

Recombinant models for assessing the role of GSTM1 in styrene-7,8-oxide mutagenicity

, 2015
Styrene-7,8-oxide (SO) is a highly reactive epoxide able to undergo reactions with endogenous nucleophiles, such as DNA. SO is inactivated by glutathione-S-transferase M1 (GSTM1).
Sanderson, Barbara, Shield, Alison
core   +1 more source

GSTM1 and GSTT1 Gene Polymorphisms with Gallbladder Carcinoma

Cellular and Molecular Biology, 2022
Jianming, Fang, Fazhuang, Fang, Jianxin, Huang, Xiaodong, Zhang, Hongjuan, Wang   +4 more
openaire   +2 more sources