Results 91 to 100 of about 5,937 (164)

Association of the glutathione s-transferase m1, t1 polymorphisms with cancer: evidence from a meta-analysis.

PLoS ONE, 2013
BackgroundGlutathione S-transferases (GSTs) are a family of multifunctional enzymes that are involved in the metabolism of many xenobiotics, including a wide range of environmental carcinogens.
Jianzheng Fang, Shangqian Wang, Shengli Zhang, Shifeng Su, Zhen Song, Yunfei Deng, Hongqing Cui, Hainan Wang, Yi Zhang, Jian Qian, Jinbao Gu, Bianjiang Liu, Pengchao Li, Rui Zhang, Xinnong Liu, Zengjun Wang   +15 more
doaj   +1 more source

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

Advanced Science
Abstract Cellular senescence is a hallmark of aging and the accumulation of senescent cells (SnCs) accelerates the aging process, contributing to aging‐related organ disorders. The PRDF1 and RIZ1 homology domain (PRDM) protein exhibits robust transcriptional regulatory activities and governs a wide range of ...
Qian Yuan, Yuting Zhu, Ben Tang, Yaru Xie, Mingcun Hu, Hua Su, Youhua Liu, Chun Zhang   +7 more
openaire   +3 more sources

Influence of glutathione S‐transferases (GSTM1, GSTT1, and GSTP1) genetic polymorphisms and smoking on susceptibility risk of chronic myeloid leukemia and treatment response

Molecular Genetics & Genomic Medicine, 2019
Background Glutathione S‐transferases (GSTs) polymorphisms may impact on chronic myeloid leukemia (CML) risk or heterogeneous responses to Imatinib mesylate (IM).
Golale Rostami, Dlnya Assad, Fatemeh Ghadyani, Mohammad Hamid, Amirhossien Karami, Hasan Jalaeikhoo, Ramezan Ali Kalahroodi   +6 more
doaj   +1 more source

GSTM1 polymorphism and oral leukoplakia

Journal of Oral Pathology & Medicine, 2006
Background:  Molecular epidemiological studies have now provided evidence that an individual susceptibility to cancer is mediated by genetic and environmental factors. Genetic polymorphisms have been described for enzymes involved in the metabolism of tobacco carcinogens and cancer risk is determined by the degree of expression and/or activity of ...
Duarte, Eliza Carla Barroso, da Silva, Marina Sena Lopes, Gomez, Marcus Vinícius, Gomez, Ricardo Santiago   +3 more
openaire   +3 more sources

No contribution of GSTM1 and GSTT1 null genotypes to the risk of neutropenia due to benzene exposure in Southeastern Brazil [PDF]

, 2009
Exposure to benzene has been associated with haematological diseases such as neutropenia (NEB) and acute myeloid leukaemia (AML). We tested whether the null genotypes of the GSTM1 and GSTT1 genes, involved in benzene inactivation, altered the risk for ...
Lorand-Metze, Irene, Helvia Nascimento, Saad, Sara Teresinha Ollala, Carmen Silvia Passos Lima, Nascimento, Helvia, Fernando Ferreira Costa, Costa, Fernando Ferreira, Sara Teresinha Ollala Saad, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob, Irene Lorand-Metze, Gustavo Jacob Lourenço   +11 more
core   +1 more source

Роль полиморфизма генов GSTT1 и GSTM1 в течении туберкулёза лёгких

, 2010
У роботі наведена частота, з якою зустрічаються деллеції генів глутатіон-s-трансфераз М1 (GSTM1) та Т1 (GSTT1) у хворих (n=115) на вперше діагностований легеневий туберкульоз мешканців Одеської області.
Chesnokova, M. M., Чеснокова, М. М., Сметюк, А. А., Бажора, Ю. І., Сметюк, О. О., Bazhora, Yu. I., Smetyuk, A. A., Бажора, Ю. И.   +7 more
core  

The GSTM1 and GSTT1 Null Genotypes Increase the Risk for Type 2 Diabetes Mellitus and the Subsequent Development of Diabetic Complications: A Meta-analysis

, 2018
Background:Studies pertaining to association of GSTM1 and GSTT1 null genotypes with risk of T2DM and its complications were often inconclusive, thus spurring the present study.Methods:Meta-analysis of 25 studies for evaluating the role of GSTM1/GSTT1 ...
Aditi Bhowmik, Sambuddha Das, Yashmin Choudhury, Sankar Kumar Ghosh, Sayantan Nath   +4 more
core   +1 more source

Results of meta-analysis of GSTM1 null polymorphism.

, 2013
Results of meta-analysis of GSTM1 null polymorphism.
Josephine Aguilar (462238), Rui Chen (95310), Tong Meng (462237), Shancheng Ren (121352), Yinghao Sun (121372)   +4 more
core   +1 more source

The Prevalence of the Genetic Polymorphism of GSTM1, GSTT1 and GSTP1 and Its Relationship with Clinical Criteria of Multiple Sclerosis (MS) Patients in Tehran

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2019
BACKGROUND AND OBJECTIVE: Multiple Sclerosis is the chronic inflammation of central nervous system with demyelinated lesions in the brain and spinal cord. The genetic polymorphisms associated with glutathione S-transferase enzymes involved in antioxidant
M Aliomrani, MA Sahraian, MR Khoshayand, T Danesh Seta, M Sharifzadeh, MH Ghahremani   +5 more
doaj  

Association between Dietary Patterns and Atopic Dermatitis in Relation to GSTM1 and GSTT1 Polymorphisms in Young Children

, 2015
Previous research suggests the association of glutathione S-transferase (GST) gene polymorphisms or diet, but no interactions between these factors in atopic dermatitis (AD).
Sung-Ok Kwon, Hyogin Ahn, Hyojung Hwang, Se-Young Oh, Jayong Chung, Soo-Jong Hong   +5 more
core   +1 more source