Results 111 to 120 of about 5,937 (164)

GSTM1 null genotype in COPD and lung cancer: evidence of a modifier or confounding effect?

, 2011
Robert P Young1,2, Raewyn J Hopkins1, Bryan A Hay1, Gregory D Gamble11Schools of Biological Science and Health Sciences, University of Auckland, 2Department of Medicine, Auckland City Hospital, Auckland, New ZealandBackground: Studies over the past two ...
Hay BA, Young RP, Gamble GD, Hopkins RJ
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GSTM1 and CYP2D6 genotype frequencies in patients with pituitary tumours: effects on P53, ras and gsp.

, 1995
We describe studies to determine if susceptibility to pituitary tumours is associated with the putatively high risk GSTM1 null and CYP2D6 EM genotypes. Frequency distributions of these genotypes were similar in cases and controls though the frequency of ...
Fryer, Anthony A., Strange, Richard C., Boscaro, Marco, Alldersea, Julie, Buckley, Nicola, Perrett, Christopher W., Scanarini, Massimilio, Pistorello, Matteo, Gilford, Janice, Jones, Peter, Clayton, Richard N., Bates, Andrew S.   +11 more
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Cumulative meta-analysis of the association between GSTM1 null genotype and lung cancer susceptibility.

, 2014
(a) publication time cumulative meta-analysis of GSTM1 variants and lung cancer risk; (b) sample size cumulative meta-analysis of GSTM1 variants and lung cancer risk.
Baobo Zou (380154), Jianmin Jiang (488872), Xia Yue (600754), Guochuan Mao (545531), Kui Liu (247249), Ting Ma (499742), Jian Chen (15340), Xialu Lin (380151), Huiqin Wang (600755), Jinshun Zhao (80435), Liyuan Han (600753), Guixiu Jin (600756), Lu Zhang (50563), Qi Zhou (7408)   +13 more
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Role of glutathione S-transferase Mu (GSTM1) in styrene-7,8-oxide toxicity and mutagenicity

, 2001
In the human glutathione S-transferase (GST) mu gene family, homozygous deletion of GSTM1 is the null phenotype (frequency of ∼50% in Caucasians).
Sanderson, Barbara J S, Shield, Alison J.; id_orcid   +1 more
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GSTM1 Gene [PDF]

, 2020
openaire   +1 more source

GSTM1, GSTT1 and EPHX1 gene polymorphisms and susceptibility to COPD in a sample of Egyptian population

, 2015
BackgroundGene polymorphisms and COPD susceptibility have been paid special attention and were explored in a large number of studies. The results varied between studies and populations.
Ramadan M. Bakr, Mohamed A. Zamzam, Shimaa M. Abozeid, Rabab A. El Wahsh, Enas S. Essa   +4 more
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Evaluation of the Importance of Genetic Polymorphisms in Genes Expressing Cancer-Metabolizing Enzymes (Cyp1a1 and Gstm1) in Oral Submucous Fibrosis

Journal of Pharmacy and Bioallied Sciences
Background: Genetic polymorphisms are common and contribute significantly to human illnesses. Aim: This study was carried out to evaluate the importance of genetic variations in the genes expressing cancer-metabolizing enzymes (CYP1A1 and GSTM1) in ...
Devina Pradhan, Tarang Mehta, Arpita Srivastava, Deepak Patel, Kailash Chandra Dash, Vidya Hittalamani, Ramanpal Singh Makkad   +6 more
doaj   +1 more source

Impact of the deletion glutathione S-transferase (class Mu) on lung cancer risk among smokers

The Egyptian Journal of Bronchology
Background The results of several studies assessing the effect of the glutathione S-transferase class Mu 1 (GSTM1) null variant on the genetic susceptibility of tobacco-related cancers have been conflicting. In this work, we aim to identify the impact of
Gehan Hamdy, Ahmed Gharib, Nahed Abdel Moneim Emara, Eman Mahmoud Hassan Attia, Mohamed Fathy Hussein, Reem Ibrahim Elkorashy, Nada Ezzeldin Gomaa   +6 more
doaj   +1 more source

GSTM1 wt Allele [PDF]

, 2020
openaire   +1 more source

Nullity of GSTT1/GSTM1 related to pesticides is associated with Parkinson's disease

, 2017
Fatores genéticos e ambientais influenciam a patogênese da doença de Parkinson (DP). Variantes genéticas das enzimas glutationa S-transferases (GST) parecem estar envolvidas com a doença.
Longo, Gabriela dos Santos, Gregorio, Michele Lima, Nakazone, Marcelo Arruda, Martins, Denise Poltronieri, Amorim, Gisele Sousa, Tognola, Waldir Antonio, Mazeti, Camila Montoro, Souza, Doroteia Rossi Silva, Florim, Greiciane Maria da Silva, Oliveira, Fabio de Nazare, Pinhel, Marcela Augusta de Souza, Sado, Caroline Leiko   +11 more
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