Results 81 to 90 of about 5,937 (164)

The influence of glutathione S-transferases M1 and M3 on the development of bladder cancer [PDF]

Problem: Cigarette smoking is the most important risk factor of transitional cell carcinoma of the urinary bladder. The effect of the glutathione S- transferases M1 (GSTM1) and M3 (GSTM3) on the influence of this risk factor was investigated.
Golka, Klaus, Bolt, Hermann M., Selinski, Silvia, Schmidt, Tobias   +3 more
core  

Gstm1 and liver iron content in children with sickle cell anemia and iron overload [PDF]

, 2019
Chronic blood transfusions in patients with sickle cell anemia (SCA) cause iron overload, which occurs with a degree of interpatient variability in serum ferritin and liver iron content (LIC).
Claudia M. Hillenbrand, Jonathan M. Flanagan, McCarville, Beth M., Bi, W, Guolian Kang, Martha Villavicencio, Kristine R. Crews, Crews, KR, Tipirneni-Sajja, Aaryani, Ding, Juan, Loeffler, Ralf B., Wenjian Bi, Crews, Kristine R., Aaryani Tipirneni-Sajja, Latika Puri, Tipirneni-Sajja, A, Juan Ding, McCarville, BM, Bi, Wenjian, Ding, J, Puri, L, Hankins, JS, Villavicencio, M, Jane S. Hankins, Kang, G, Kang, Guolian, Ralf B. Loeffler, Hillenbrand, CM ; https://orcid.org/, Puri, Latika, Beth M. McCarville, Flanagan, JM, Villavicencio, Martha, Loeffler, RB ; https://orcid.org/, Flanagan, Jonathan M.   +33 more
core   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

The relationship between genetic polymorphism of GSTM1 and the outcome of chemotherapy in Chinese patients with primary lung cancer

Chinese Journal of Lung Cancer, 2008
Background and objective GSTM1 takes part in the metabolism of environmental pollutants such as benzopyrene other polycyclic aromatic hydrocarbons and anticancer drugs and so on.
Baitang LAI, Hui WANG, Weiying LI, Yanfei GU   +3 more
doaj  

Increased Risk of Acute Lymphoblastic Leukemia in Adult Patients with GSTM1 Null Genetic Polymorphism

Pharmacogenomics and Personalized Medicine, 2022
Ezeldine K Abdalhabib,1 Badr Alzahrani,1 Fehaid Alanazi,1 Abdulrahman Algarni,2 Ibrahim Khider Ibrahim,3 Hozifa A Mohamed,4,5 Hassan A Hamali,6 Abdullah A Mobarki,6 Gasim Dobie,6 Muhammad Saboor6,7 1Department of Clinical Laboratory Sciences, College of ...
Abdalhabib EK, Alzahrani B, Alanazi F, Algarni A, Ibrahim IK, Mohamed HA, Hamali HA, Mobarki AA, Dobie G, Saboor M   +9 more
doaj  

GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer

, 2013
Xuemei Zhang,1 Maosheng Huang,2 Xifeng Wu,2 Susan Kadlubar,1 Jie Lin,2 Xinfeng Yu,1 Chunyang Fan,3 Baitang Ning,4 Fred F Kadlubar1†1University of Arkansas for Medical Sciences, Little Rock, Arkansas, 2The University of Texas MD Anderson Cancer
Ning B, Zhang X, Huang M, Kadlubar FF, Lin J, Kadlubar S, Yu X, Fan C, Wu X   +8 more
core  

Glutathione S-transferase M1 and T1 genes deletion polymorphisms and risk of developing essential hypertension: a case-control study in Burkina Faso population (West Africa)

BMC Medical Genetics, 2020
Background Glutathione S-transferases play a key role in the detoxification of persistent oxidative stress products which are one of several risks factors that may be associated with many types of disease processes such as cancer, diabetes, and ...
Herman Karim Sombié, Abel Pegdwendé Sorgho, Jonas Koudougou Kologo, Abdoul Karim Ouattara, Sakinata Yaméogo, Albert Théophane Yonli, Florencia Wendkuuni Djigma, Daméhan Tchelougou, Dogfounianalo Somda, Isabelle Touwendpoulimdé Kiendrébéogo, Prosper Bado, Bolni Marius Nagalo, Youssoufou Nagabila, Enagnon Tiémoko Herman Donald Adoko, Patrice Zabsonré, Hassanata Millogo, Jacques Simporé   +16 more
doaj   +1 more source

Connective tissue and genetics in the pathogenesis of rectal prolapse: A scoping review

Colorectal Disease, Volume 28, Issue 9, September 2026.
Abstract Aim Rectal prolapse can occur in individuals who lack the established risk factors (constipation, obstetric trauma and advanced age). A recognised association with hereditary connective tissue diseases may indicate a role for variants in connective tissue‐related genes in the pathogenesis of the disease.
Matthew Davenport, Alexander O'Connor, William G. Newman, Andrew P. Morris, Abhiram Sharma, Gemma Faulkner, Dipesh H. Vasant, John McLaughlin, Edward Kiff, Karen Telford   +9 more
wiley   +1 more source

GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

, 2015
The glutathione S-transferase (GST) family consists of phase II detoxification enzymes that catalyze the conjugation of toxic substances, such as chemotherapeutic agents, to glutathione.
Rodrigues, FFO, Aoki, T, Santos, RE, Oliveira, AL, Longui, CA, Rocha, MN, Melo, MB   +6 more
core   +1 more source

Detection of GSTM1 Polymorphism in Patient with Nasopharyngeal Carcinoma by Real-Time PCR

Siriraj Medical Journal, 2008
Objective: To investigate whether the real-time polymerase chain reaction (R-PCR) assay with SYBR green I and melting curve analysis could be used for glutathione S-transferase M1 gene (GSTM1) polymorphism detection in Thai nasopharyngeal carcinoma (NPC)
Danai Tiwawech, Somjin Chindavijak, Anant Karalak, Takafumi Ishida, Yaninee Jarratwisrutpom   +4 more
doaj