Results 61 to 70 of about 5,937 (164)

Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia

Pharmacogenomics and Personalized Medicine, 2021
Ezeldine K Abdalhabib,1 Denise E Jackson,2 Badr Alzahrani,1 Elyasa M Elfaki,1 Alneil Hamza,1 Fehaid Alanazi,1 Elryah I Ali,3 Abdulrahman Algarni,3 Ibrahim Khider Ibrahim,4 Muhammad Saboor5,6 1Department of Clinical Laboratory Sciences, College of Applied
Abdalhabib EK, Jackson DE, Alzahrani B, Elfaki EM, Hamza A, Alanazi F, Ali EI, Algarni A, Ibrahim IK, Saboor M   +9 more
doaj  

Association of oxidative stress-related gst gene polymorphisms with periodontitis susceptibility: A systematic review and meta-analysis [PDF]

Journal of Advanced Periodontology and Implant Dentistry
Introduction: Periodontitis is a prevalent inflammatory disease influenced by both genetic and environmental factors. Among genetic determinants, polymorphisms in oxidative stress-related g e n e s — p a r t i c u l a r l y GSTM1, GSTT1, and GSTP1 ...
Paria Motahari, Negin Neshanifard
doaj   +1 more source

RAF1 Promotes Gstt1‐Mediated Ferroptosis by Promoting KDM1A Recruitment to Facilitate Pilocarpine‐Induced Acute Seizure‐Associated Neuronal Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In the hippocampus of mice with pilocarpine‐induced acute seizures and in glutamate‐treated neuronal cell lines, the mRNA and protein levels of RAF1 were significantly increased. RAF1 interacts with the KDM1A and recruits it to the promoter of Gstt1, thereby inhibiting the transcription of Gstt1.
Tiantian Lu, Yonghong Feng, Xiuling Chen, Liyan Shen, Min Liu, Yanping Jia   +5 more
wiley   +1 more source

PCR primers for GSTM1 and GSTT1.

, 2014
PCR primers for GSTM1 and GSTT1.
Chen Shen (415899), Wei-wei Jiao (2198146), An-xia Jiao (677097), Qing-qin Yin (431854), Wei Zhao (14321), A-dong Shen (431857), Jing Xiao (356412), Dan Shen (380488), Jian-ling Tian (535862), Evelyne Jacqz-Aigrain (362302), Xi-rong Wu (5655628), Lin Sun (105539), Fang Liu (13271), Hui Qi (460415)   +13 more
core   +1 more source

Association between null Genotypes of glutathione S-transferase M1 and T1 and susceptibility to systemic lupus erythematosus: A meta-analysis [PDF]

Scripta Medica
Oxidative stress is involved in the development of systemic lupus erythematosus (SLE). It is well known that activity of the glutathione S-transferase superfamily has a protective effect against oxidative stress.
Saadat Mostafa
doaj   +1 more source

Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Man Chen, Nana Ding, Xingmin Qiu, Lan Li, Yali Guo, Rongyanqi Wang, Xiaowei Mo, Tan Zou, Shangzhen Yu, Xiaojuan Li, Jiaxu Chen   +10 more
wiley   +1 more source

An association between resistant hypertension and the null GSTM1 genotype [PDF]

Journal of Human Hypertension, 2009
Reduction in expression levels of glutathione S-transferase (GST) mu type 1 (GSTM1) in stroke-prone spontaneously hypertensive rats has recently been reported. GSTM1 genotype was evaluated in 49 patients with resistant hypertension and compared with selected patients with controlled hypertension (n=232) and healthy participants (n=110).
I, Cruz-Gonzalez, E, Corral, M, Sanchez-Ledesma, A, Sanchez-Rodriguez, C, Martin-Luengo, R, Gonzalez-Sarmiento   +5 more
openaire   +2 more sources

Single‐Cell Analysis of Cartilage‐Derived Cells Identifies Diverse Populations and a Cholesterol/ER‐Stress Chondrocyte Subset in Knee OA

Journal of Orthopaedic Research, Volume 44, Issue 10, October 2026.
ABSTRACT This study aimed to elucidate the cellular and molecular mechanisms underlying knee osteoarthritis pathogenesis by analyzing chondrocyte populations and their spatial distribution using single‐cell RNA sequencing (scRNA‐seq). Knee cartilage cells underwent scRNA‐seq.
Yu Kobori, Kohei Nishitani, Hiroyuki Yoshitomi, Akinori Murakami, Kazuki Ichiyanagi, Shigeo Yoshida, Jiu Tanaka, Shinichi Kuriyama, Shinichiro Nakamura, Akio Sakamoto, Takashi Noguchi, Yugo Morita, Takashi Sono, Takayuki Fujii, Koichi Murata, Junya Toguchida, Hideki Ueno, Yasuhiro Murakawa, Chikashi Terao, Shuichi Matsuda   +19 more
wiley   +1 more source

Genome‐Wide Association Studies of Hospitalized Influenza Identify Four Risk Loci and Reveal Shared and Unique Genetic Factors Compared With COVID‐19

Influenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Background Influenza remains a significant global health burden, potentially leading to hospitalization and mortality. Although previous studies have explored genetic susceptibility to influenza infection, the genetic basis of influenza hospitalization and its relationship with respiratory diseases like COVID‐19 remain poorly understood ...
Xiao Xue, Yaning Feng, Yu‐Ping Lin, Pui‐Ching Chan, Hon‐Cheong So   +4 more
wiley   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source