Results 81 to 90 of about 9,099 (167)

Association analysis of GSTT1, GSTM1 genotype polymorphisms and serum total GST activity with ischemic stroke risk

, 2010
Oxidative stress plays a major role in pathogenesis of atherosclerosis which is responsible for stroke. Glutathione S-transferases (GSTs) detoxify metabolites produced by oxidative stress within the cell and protect the cells against injury.
Semai Bek, ADALI, ORHAN, Demirkaya, Seref, Birsen Can Demirdöğen, Demirdogen, Birsen Can, Şeref Demirkaya, Orhan Adalı, Turkanoglu, Aysun, Aysun Türkanoğlu, Bek, Semai, Adalı, Orhan   +10 more
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Association of GSTP1, GSTT1 and GSTM1 Gene Variants with Coronary Artery Disease in Iranian Population: A Case–Control Study

International Journal of General Medicine, 2020
Alemeh Pourkeramati,1 Ehsan Zare Mehrjardi,1 Masoud Dehghan Tezerjani,2 Seyed Morteza Seifati1 1Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran; 2Abortion Research Centre, Yazd Reproductive Sciences ...
Pourkeramati A, Zare Mehrjardi E, Dehghan Tezerjani M, Seifati SM   +3 more
doaj  

Lack of association between the glutathione-s-transferase genes (GSTT1 and GSTM1) and nasal polyposis

, 2006
Objectives: To evaluate the glutation-S-transferase (GST) polymorphisms (GSTM1 and GSTT1) in nasal polyposis (NP). Methods: The study population consisted of 102 unrelated healthy individuals and 98 patients with NP (67 without asthma, 31 with asthma ...
Öztürk, Kayhan, Çora, Tülin, Arbağ, Hamdi, Sarı, Fatih, Ulusoy, Bülent, Acar, Hasan   +5 more
core  

The role of GSTM1 and GSTT1 polymorphism in patients with renal cell carcinoma [PDF]

Journal of Medical Biochemistry, 2010
Members of the glutathione S-transferase (GST) superfamily exhibit polymorphic expression. GSTs are investigated as biomarkers of risk for various cancers, including renal cell carcinoma (RCC).
Ćorić Vesna, Plješa-Ercegovac Marija, Matić Marija, Krivić Biljana, Šuvakov Sonja, Tulić Cane, Mimić-Oka Jasmina, Simić Tatjana   +7 more
doaj  

Copy Number Variation in the GSTM1 and GSTT1 Genes and the Risk of Liver Cirrhosis in Eastern Ethiopia

The Application of Clinical Genetics, 2023
Abraham Nigussie Mekuria,1 Tamrayehu Seyoum,2 Dawit Hailu Alemayehu,2 Markos Abebe,2 Teshome Nedi,1 Tefera Abula,1 Yun Yun Gong,3 Ephrem Engidawork1 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis ...
Mekuria AN, Seyoum T, Alemayehu DH, Abebe M, Nedi T, Abula T, Gong YY, Engidawork E   +7 more
doaj  

GSTT1 is Deregulated in Left Colon Tumors

, 2014
Our aim was to determine GSTT1 expression levels in left colon tumors and paired normal tissue in order to identify specific alterations in GSTT1 mRNA levels.
Coskunpinar, Ender Mehmet, BUGRA, Dursun, CANBAY, Emel, Oltulu, Yasemin Musteri, Tiryakioglu, Necip Ozan   +4 more
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Association of GST genetic polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese population evaluated by an updated systematic meta-analysis.

PLoS ONE, 2013
BackgroundDue to the possible involvement of Glutathione S-transferase Mu-1 (GSTM1) and Glutathione S-transferase theta-1 (GSTT1) in the detoxification of environmental carcinogens, environmental toxins, and oxidative stress products, genetic ...
Kui Liu, Lu Zhang, Xialu Lin, Liangliang Chen, Hongbo Shi, Ruth Magaye, Baobo Zou, Jinshun Zhao   +7 more
doaj   +1 more source

Summary of meta-analysis of GSTM1, GSTT1 and GSTP1 polymorphisms and PCa risk.

, 2012
OR, odds ratio; CI, confidence interval.*GSTP1 the total result of after excluding three researches deviated from Hardy-Weinberg equilibrium (HWE).aGSTM1 (−/−) and GSTT1 (−/−) vs.
Mancheng Gong (117913), Wenjing Dong (117921), Ruihua An (117936), Yangyang Xu (117932), Zhirong Shi (117928), Wenjun Ni (117934)   +5 more
core   +1 more source

Genetic polymorphisms of glutathione S-transferase Mu 1, glutathione S-transferase theta 1, and glutathione S-transferase P1 in oral squamous cell carcinoma: A case-control study in Iranian population

Journal of Orofacial Sciences, 2015
Background: Gene variability related to activation and detoxification of procarcinogens affects the susceptibility to oral squamous cell carcinoma (OSCC).
Bahram Yaghmaei, Kaveh Yaghmaei, Mohammad Jafarian, Shima Golmohammadi   +3 more
doaj   +1 more source

GST (GSTM1, GSTT1, and GSTP1) polymorphisms in the genetic susceptibility of Turkish patients to cervical cancer

, 2010
Objective: This work investigates the role of glutathione S-transferase M1 (GSTM1), glutathione S-transferase T1 (GSTT1), and glutathione S-transferase P1 (GSTP1) enzymes and polymorphisms, which are found in phase II detoxification reactions in the ...

core   +1 more source