Results 201 to 210 of about 190,941 (249)

A Streamlined In Vitro mRNA Production Evaluation for mRNA-Based Vaccines and Therapeutics. [PDF]

Methods Protoc
Madia V, Minesso S, Franceschi V, Donofrio G.   +3 more
europepmc   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Manganese activates the CBASS immunity to protect bacteria from phage infection. [PDF]

mBio
Wang X, Li Y, Wang X, Zhang W, Liu M, Hao X, Chen S, Chang T, Wu C, Hao C, Song L, Ni H, Chen Y, Shen X, Xu L.   +14 more
europepmc   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

The FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge, Srđan Vujinović, Alexander Scholten, Karl‐Wilhelm Koch   +3 more
wiley   +1 more source

IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope. [PDF]

Cancer Sci
Ogawa-Iio A, Takeuchi K, Shigemi K, Genoveso MJ, Niitsu H, Koh I, Ota Y, Yamane K, Hinoi T, Osaka N, Oshima M, Ishikawa T, Mizuno T, Natsumeda M, Tateishi K, Hashizume R, Osuka S, Goyama S, Yasuda T, Senda T, Sasaki AT.   +20 more
europepmc   +1 more source

Activation of phospholipase C beta 4 by heterotrimeric GTP-binding proteins.

, 1994
Huiping Jiang, Ding Wen Wu, Melvin I. Simon   +2 more
openalex   +1 more source

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

International Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian, Arnavaz Akhzarmehr, Charise Dallazem Bertol   +2 more
wiley   +1 more source

Structural insights into GM4951 as a lipid droplet GTPase regulating hepatic lipid metabolism. [PDF]

Nat Commun
Raj R, Jiang Y, Jha RK, Moresco EMY, Joshi H, Zhang Z, Beutler B.   +6 more
europepmc   +1 more source

Efficacy and safety of SGLT2 inhibitor on insulin resistance and hyperglycemia in Werner syndrome—A case report

Journal of Diabetes Investigation, EarlyView.
Dapagliflozin improved glycemic control and insulin resistance while preserving skeletal muscle mass, body weight, and renal function over 2 years in a patient with Werner syndrome. These findings suggest that SGLT2 inhibitors may be used safely with beneficial effects in patients with Werner syndrome.
Takashi Yagi, Daisuke Aotani, Chie Hasegawa, Yuki Shimizu, Hiroyuki Koyama, Yoshiro Maezawa, Koutaro Yokote, Tomohiro Tanaka   +7 more
wiley   +1 more source

The mechanism of thioamide formation by the YcfA-YcfC system in 6-thioguanine biosynthesis. [PDF]

Nat Commun
Zhang L, Dou C, Yan W, Chen P, Jia X, Zhang N, Zhou D, Long Z, Zhang L, Zhu X, Cheng W.   +10 more
europepmc   +1 more source