Results 241 to 250 of about 328,032 (283)

Disabling posttranscriptional regulation of AGO2 results in enhanced viral resistance

New Phytologist, EarlyView.
Márta Ludman, Károly Fátyol
wiley   +1 more source

α‐Synuclein oligomers slow down action potential firing and enhance dopamine release by increasing Cav2.2 currents in midbrain dopaminergic neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Left: the spontaneous quantal release of dopamine (DA) occurs at very low frequency in control conditions. Right: exogenous α‐synuclein potentiates Cav2.2 currents and DA release but drastically reduces the spontaneous firing rate of substantia nigra DA neurons.
Giulia Tomagra, Anthony Battaglia, Claudio Franchino, Sara Bonzano, Federico Picollo, Giuseppe Chiantia, Antonio de Iure, Paolo Calabresi, Barbara Picconi, Emilio Carbone, Silvia De Marchis, Andrea Marcantoni, Valentina Carabelli   +12 more
wiley   +1 more source

Mycophenolate mofetil reduces the branching of microglial processes. [PDF]

Mol Brain
Teruya RI, Ueda K, Taketomi T, Yamamoto T, Yamashita N, Konno H, Tsuruta F.   +6 more
europepmc   +1 more source

PrP^C-Neutralizing Antibody Confers an Additive Benefit in Combination with 5-Fluorouracil in KRAS-Mutant Colorectal Cancer Models, Associated with Reduced RAS-GTP and AKT/ERK Phosphorylation. [PDF]

Int J Mol Sci
Lee JK, Yoon JY, Lee JY, Lee SH.
europepmc   +1 more source

Membrane Constriction by Dynamin through GTP-Driven Conformational Changes from Coarse-Grained Molecular Dynamics Simulations. [PDF]

J Phys Chem Lett
Mahmood MI, Kubo S, Noguchi H, Okazaki KI.   +3 more
europepmc   +1 more source

Guanine nucleotide directed co-assembly with Pt-complexes for tailoring chiroptical properties and multimodal molecular recognition. [PDF]

Chem Sci
Xiao J, Zeng F, Luo ZW, Yang B, Song J, Duan P, Jin X, Chen Y, Yu ZQ.   +8 more
europepmc   +1 more source

Crystal structure of the class V GTP-binding RNA aptamer bound to its ligand: GTP recognition by a topologically complex intermolecular G-quadruplex. [PDF]

Nucleic Acids Res
Stafflinger H, Neißner K, Bartsch S, Pichler AK, Bartosik K, Dhamotharan K, Abele R, Duchardt-Ferner E, Micura R, Schindelin H, Wöhnert J.   +10 more
europepmc   +1 more source

Pan-KRAS inhibition: unlocking broad-spectrum targeted therapy for <i>KRAS</i>-mutant cancers. [PDF]

Cancer Biol Med
Feng J, Xiao X, Lian Z, Zhang A, Pang X.
europepmc   +1 more source