Results 1 to 10 of about 2,286 (161)

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1993
Cotransfection assays were used to show that the members of the GTP-binding protein Gq class of alpha subunits could activate phospholipase C (PLC) beta 2.
Dianqing Wu, A. Katz, Melvin I. Simon
semanticscholar   +3 more sources

GTP-Binding Protein RAD

Definitions, 2020
GTP-binding protein RAD (308 aa, ~33 kDa) is encoded by the human RRAD gene. This protein is involved in the regulation of calmodulin- and voltage-dependent L-type calcium channel subunit alpha-1C-mediated signaling.

semanticscholar   +1 more source

Developmental Changes of Trimeric GTP-binding Protein in Porcine Brain and Immune System

, 1998
KovariI H., F. KovariI, V. ZiZkovsky, J. Velek: Developmental Changes oj Trimeric GTP-binding Protein in Porcine Brain and Immune System. Acta vet. Bmo 1998,67: 15-20.
H. Kovářů, F. Kovářů, V. Žižkovský, J. Velek   +3 more
semanticscholar   +1 more source

G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding

Signal Transduction and Targeted Therapy
A recent report from the Skiniotis group, 1 published in Nature , provides fascinating insight into the molecular choreography underlying a quintessential cellular signaling mechanism: G protein-mediated signal transduction.
E. Kostenis, Lars Jürgenliemke, J. Alenfelder   +2 more
semanticscholar   +1 more source

Identification of two novel GTP-binding protein alpha-subunits that lack apparent ADP-ribosylation sites for pertussis toxin.

Journal of Biological Chemistry, 1991
F. Nakamura, K. Ogata, K. Shiozaki, K. Kameyama, K. Ôhara, T. Haga, T. Nukada   +6 more
semanticscholar   +1 more source

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

Proceedings of the National Academy of Sciences of the United States of America, 1988
H. Fong, K. Yoshimoto, P. Eversole-Cire, Melvin I. Simon   +3 more
semanticscholar   +1 more source

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

Proceedings of the National Academy of Sciences of the United States of America, 1990
Teresa L. Z. Jones, W. Simonds, J. J. Merendino, Mark R. Brann, Allen M. Spiegel   +4 more
semanticscholar   +1 more source

At least three alternatively spliced mRNAs encoding two alpha subunits of the Go GTP-binding protein can be expressed in a single tissue.

Journal of Biological Chemistry, 1990
P. Bertrand, J. Sanford, U. Rudolph, J. Codina, L. Birnbaumer   +4 more
semanticscholar   +1 more source

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling. [PDF]

Nat Commun, 2022
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y.   +11 more
europepmc   +1 more source

Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

Proceedings of the National Academy of Sciences of the United States of America, 1986
T. Michel, J. Winslow, J. Smith, J. Seidman, E. Neer   +4 more
semanticscholar   +1 more source