Results 161 to 170 of about 142,607 (261)

COST1 stimulates RHD3 GTPase activity to maintain ER morphology and plant growth in <i>Arabidopsis</i>. [PDF]

Sci Adv
Wang J, Jiang J, Ren J, Zhao Y, Zhang Y, Feng D, Li Y, Zhang Q, Niu Y, Zhang X, Xu K, Sun J, Wang P, Zheng H, Bassham DC, Wang C, Hu J, Bao Y.   +17 more
europepmc   +1 more source

Activation of GTP-binding proteins

Shinzo, 1993
Takahashi, Katsunobu, Tomita, Urara, Katada, Toshiaki   +2 more
openaire   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

Journal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab-binding domain. [PDF]

Protein Sci
Nielipińska D, Orlikowska M, Nielipiński M, Sekuła B, Błażewska KM, Gendaszewska-Darmach E, Pietrzyk-Brzezińska AJ.   +6 more
europepmc   +1 more source

Targeted Modulation of Eukaryotic Release Factor 1 (OseRF1) by an RNA Aptamer Enhances Drought Adaptation in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought stress severely restricts rice productivity, necessitating strategies to enhance stress resilience. Here, we identify translation termination as a tunable regulatory node for stress adaptation. Using 25 rounds of SELEX, we isolated RTAR, an RNA aptamer that binds the rice eukaryotic release factor 1 (OseRF1) with nanomolar affinity ...
Shuangfeng Dai, Mingming Chen, Haomin Chen, Yuantao Ye, Hong Huang, Renrong Zhang, Zhenyu Guo, Yongxiang Huang   +7 more
wiley   +1 more source

Synthesis and Biochemical Characterization of Investigational Pyrazolopyrimidine-Based Allosteric KRAS Modulators. [PDF]

ACS Med Chem Lett
Pagba CV, Dilsha K, Ojha R, Jakubec J, Liang X, Sianoya AC, Medina PMB, Gilbertson S, Gorfe AA.   +8 more
europepmc   +1 more source

Effects of exercise in a fed or fasted state on mitochondrial dynamics regulators in the skeletal muscle of recreationally active males

Experimental Physiology, EarlyView.
Abstract Exercise and nutritional modulation favourably alter mitochondrial quantity and quality in skeletal muscle. Mitochondrial dynamics, the coordination of fission and fusion events, are poised to mediate key aspects of organelle adaptation that arise from exercise.
Elya J. Ritenis, Christos G. Stathis, Matthew B. Cooke, Stephen Keenan, Andrew Philp, Donny M. Camera   +5 more
wiley   +1 more source

RANBP3 and RAN orchestrate CRM1-mediated nuclear export of hepatitis B virus RNAs. [PDF]

J Virol
Wang M, Chen Q, Zheng Y, Yin J, Zhu G, Zhao K, Xu Z, Hua R, Zhou M, Zhang L, Zhao G, Yang S, Amat Z, Xia Y, Cheng X.   +14 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

SspE-mediated immune defense: GTP hydrolysis as an allosteric switch coupling phosphorothioate recognition to DNA cleavage. [PDF]

mBio
Zhou Y, Zhang K, He Y, Gao H, Zhong Y, Wang X, Wang M, Wang L, Chen S.   +8 more
europepmc   +1 more source