Results 171 to 180 of about 1,111,922 (385)
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling+5 more
wiley +1 more source
Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes [published erratum appears in J Neurosci 1989 Apr;9(4):following Table of Contents] [PDF]
Sylvie Peraldi+9 more
openalex +1 more source
Discovery and first total synthesis of (−)‐glycybridin B via a five‐step route utilizing a key chalcone intermediate. Initially identified through a pharmacophore screening as a potential tubulin binder, this natural product serves as a tool compound to explore structure‐activity relationships related to microtubule targeting and anticancer potential ...
Alice Maiocchi+14 more
wiley +1 more source
The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou+6 more
wiley +1 more source
GTPase activity of small GTP-binding proteins in HL-60 membranes is stimulated by arachidonic acid [PDF]
Erzsébet Ligeti+4 more
openalex +1 more source
GTP‐binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
X. Bustelo+2 more
semanticscholar +1 more source
Interaction Between Actin and Microtubules During Plant Development
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu+3 more
wiley +1 more source
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah+2 more
wiley +1 more source