Results 261 to 270 of about 232,253 (352)
Disabling posttranscriptional regulation of AGO2 results in enhanced viral resistance
New Phytologist, EarlyView.
Márta Ludman, Károly Fátyol
wiley +1 more source
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
G12 mutations rewire allosteric communication at the Ras-RalGDS interface. [PDF]
Demirbas E +5 more
europepmc +1 more source
Low molecular weight GTP-binding proteins in human neutrophil granule membranes.
Mark R. Philips +5 more
openalex +1 more source
ABSTRACT Heterozygous de novo and inherited biallelic pathogenic variants in DNM1 have been reported in association with autosomal dominant (AD) and autosomal recessive (AR) developmental and epileptic encephalopathy, respectively, due to aberrant dynamin function or expression, with each inheritance pattern associated with a different mechanism of ...
Andy Drackley +7 more
wiley +1 more source
Synthetic gene circuits that selectively target RAS-driven cancers. [PDF]
Senn GV, Nissen L, Benenson Y.
europepmc +1 more source
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias +7 more
wiley +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Binding of the brain G protein G⍺<sub>o</sub> to its potential effector RASA3 is promoted by Ca<sup>2</sup>. [PDF]
Bell HAS +4 more
europepmc +1 more source

