Results 241 to 250 of about 231,218 (308)

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Unfolded Protein Response in Glioblastoma: Mechanisms of Proteostasis, Tumor Adaptation, and Therapeutic Relevance. [PDF]

Neurochem Res
Caglar HO.
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Reduced SH3RF3 May Protect Against Alzheimer's Disease by Lowering Microglial Pro‐Inflammatory Responses via Modulation of JNK and NFkB Signaling

Glia, Volume 74, Issue 7, July 2026.
SNPs in SH3RF3 decrease the age of onset of Alzheimer's disease (AD). Reduced SH3RF3 blunts human microglial JNK and NFkB signaling and downstream inflammatory cytokine production, which may partially explain how SH3RF3 SNPs protect against AD. ABSTRACT Understanding how high‐risk individuals are protected from Alzheimer's disease (AD) may illuminate ...
Ronak Patel, Rong Cheng, Christopher L. Cardona, Ellen Angeles, Gunjandeep Singh, Sabrina Miller, Archana Ashok, Andrew F. Teich, Angel Piriz, Aleyda Maldonado, Ivonne Z. Jiménez‐Velázquez, Richard Mayeux, Joseph H. Lee, Andrew A. Sproul   +13 more
wiley   +1 more source

The eIF5-mimic protein 5MP1: a regulator of translation stringency and a multifaceted oncogene. [PDF]

J Biochem
Banerjee A, Brooke G, Ishiguro S, Asano K.   +3 more
europepmc   +1 more source

A novel OPHN1 variant associated with cyclic strabismus but in the absence of OPHN1 syndrome. [PDF]

Sci Rep
Nishina S, Kofuji S, Matsubara K, Anzai H, Hirakata K, Hanazono Y, Okamoto-Uchida Y, Hirayama J, Ito N, Fukami M, Nishina H.   +10 more
europepmc   +1 more source

Autism-linked protein POSH balances NMDAR signaling via a self-limiting kinase-scaffold loop. [PDF]

iScience
Yao M, Wang S, Zhang F, Shi L, Xu Z.
europepmc   +1 more source

Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B. [PDF]

Nat Commun
Duhay V, Tian M, Kosieradzka K, Ebner M, Lo WT, Krauss M, Sprengel HL, Voss M, Riechmann M, Savas JN, Schwake M, Haucke V, Damme M.   +12 more
europepmc   +1 more source

Induced opening of conformational switch I in GTP-bound Ran GTPase. [PDF]

Protein Sci
Czigleczki J, Dudas B, Balog E.
europepmc   +1 more source

Optimizing spatial organization of FtsZ rings for large-scale constriction in synthetic cells. [PDF]

Nat Commun
Panevska A, Šakanović A, Paccione G, Rivas G, Schwille P.   +4 more
europepmc   +1 more source