Results 261 to 270 of about 231,218 (308)

GTP-binding proteins in a cyanobacterium Anabaenacylindrica

Biochemical and Biophysical Research Communications, 1988
GTP-binding proteins were detected in a crude extract containing membrane components of Anabaena cylindrica. The crude extract was treated with 1% Lubrol PX and was fractionated by gel filtration. The binding of [35S]GTP gamma S to GTP-binding proteins was prevented in the presence of 0.1 mM GTP and in the presence of 0.1 mM ATP. Six fractions of these
M, Ohmori, K, Hasunuma, K, Furukawa
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GTP-binding Proteins and Signal Transduction

2002
Being metabolic regulators, nucleotides play many other roles rather than just providing the alphabets of the genetic code. The pyrimidine bases act as identifiers for metabolites. Purine nucleotides play their main regulatory roles in association with proteins, not metabolites.
Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham   +2 more
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The Role of GTP-Binding Proteins in Platelet Activation

Thrombosis and Haemostasis, 1991
SummaryPlatelet activation begins with the binding of an agonist to the cell surface and culminates in the events of platelet aggregation, secretion and clot formation. Recent studies have identified two large families of GTP-binding proteins in platelets that are thought to participate in the events of platelet activation. The first of these are the G
D R, Manning, L F, Brass
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Identification and isoprenylation of plant GTP-binding proteins

Plant Molecular Biology, 1996
To identify isoprenylated plant GTP-binding proteins, Arabidopsis thaliana and Nicotiana tabacum cDNA expression libraries were screened for cDNA-encoded proteins capable of binding [32P]GTP in vitro. ATGB2, an Arabidopsis homologue of the GTP-binding protein Rab2, was found to bind GTP in vitro and to be a substrate for a geranylgeranyl:protein ...
B, Biermann, S K, Randall, D N, Crowell
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GTP-binding proteins and early embryogenesis in Xenopus

Cellular Signalling, 1995
During early embryogenesis the specification of body axes and the determination of cell subtypes proceeds through cell interactions and movements which involve the decoding of various signals in a spatial and temporal manner. An increasingly abundant literature has revealed the participation of growth factors and their receptors in the induction and ...
L, Paquereau, Y, Audigier
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Small GTP-binding protein-coupled receptors

Biochemical Society Transactions, 2004
Heterotrimeric GPCRs (G-protein-coupled receptors) form the largest group of integral membrane receptor proteins and mediate diverse physiological processes. In addition to signalling via heterotrimeric G-proteins, GPCRs can also signal by interacting with various small G-proteins to regulate downstream effector pathways.
M, Bhattacharya, A V, Babwah, S S G, Ferguson   +2 more
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GTP Binding Proteins in Platelets

1999
Cells are constantly engulfed in an environment of electrical and chemical stimuli. Specific receptors enable cells to differentiate among the stimuli and relay a specific message that leads to a defined cellular response. The process that translates the stimulus-receptor interaction into an intracellular chemical message is termed signal transduction.
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Small GTP binding proteins and bacterial virulence

Microbes and Infection, 2000
Many bacterial toxins and bacterial enzymes modify small GTPases. Toxins exhibit different enzymatic activities on either the switch 1 or switch 2 domains of these small GTPases leading to inactivation or activation of such intracellular timer molecules.
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Regulation of vesicular transport by GTP-binding proteins

Current Opinion in Nephrology and Hypertension, 1995
Intracellular protein trafficking occurs in a series of transport vesicles. Vesicle trafficking is regulated both by heterotrimeric and monomeric GTP-binding proteins (G proteins). Recent studies have explored effector systems used by heterotrimeric G proteins and by monomeric ADP-ribosylation factor G proteins for regulation of vesicle budding.
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Small GTP-binding proteins as compartmental markers

Seminars in Cell Biology, 1992
Each intracellular compartment involved in the biosynthetic/secretory pathway of eukaryotic cells bears at its surface at least one small GTP-binding protein. Most of them belong to a distinct branch of the p21ras superfamily, the Sec4/Ypt1/rab family. Other proteins are members of the ARF family.
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