Results 271 to 280 of about 1,111,922 (385)
Detection of 23-27 kDa GTP-binding proteins in platelets and other cells.
R. Bhullar, R. Haslam
semanticscholar +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer. [PDF]
Dilasser F+26 more
europepmc +1 more source
Consecutive Steps of Nucleoside Triphosphate Hydrolysis Are Driving Transport of Precursor Proteins into the Endoplasmic Reticulum [PDF]
Klappa, Peter+6 more
core +1 more source
Posttranslational Modification of GTP-Binding Proteins
openaire +2 more sources
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Methods for Controlling Small GTPase Activity. [PDF]
Faulkner B, He Y, Sitrin D, Stains CI.
europepmc +1 more source
We report a 2‐year‐old male with clinical features of Takenouchi‐Kosaki syndrome, bilateral colobomas, and a de novo, likely pathogenic missense variant in CDC42. Supportive evidence includes a Cdc42 conditional knock‐out mouse model with colobomas.
Diana Brightman+11 more
wiley +1 more source
A tubulin-binding protein that preferentially binds to GDP-tubulin and promotes GTP exchange. [PDF]
Yon WJ, Ha T, Zheng Y, Pedersen RTA.
europepmc +1 more source