Results 271 to 280 of about 140,887 (291)

The Rheb family of GTP-binding proteins

Cellular Signalling, 2004
Rheb proteins represent a novel and unique family of the Ras superfamily GTP-binding proteins that is conserved from yeast to human. Biochemical studies establish that they bind and hydrolyze GTP. Molecular modeling studies reveal a few structural differences between Rheb and Ras, which may suggest that residues involved in biochemical activities ...
Paul-Joseph, Aspuria, Fuyuhiko, Tamanoi
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GTP-binding Proteins and Signal Transduction

2002
Being metabolic regulators, nucleotides play many other roles rather than just providing the alphabets of the genetic code. The pyrimidine bases act as identifiers for metabolites. Purine nucleotides play their main regulatory roles in association with proteins, not metabolites.
Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham   +2 more
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GTP-binding proteins in intracellular transport

Trends in Cell Biology, 1992
One of the most exciting recent discoveries in the area of intracellular protein transport is the finding that many organelles involved in exocytic and endocytic membrane traffic have one or more Ras-like GTP-binding proteins on their cytoplasmic face that are specific for each membranous compartment.
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GTP-Binding Proteins: Structures, interactions and relationships

Current Biology, 1994
Recently available crystal structures show that some, though not all, GTP-binding proteins have a common 'G-domain' topology, variations on which confer distinct functional properties.
T, Schweins, A, Wittinghofer
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Signal transducing gtp-binding proteins in olfaction

Comparative Biochemistry and Physiology Part A: Physiology, 1990
1. Several members of the family of heterotrimeric signal transducing GTP-binding proteins have been identified in the olfactory epithelium of vertebrates by biochemical and molecular cloning techniques. 2. Biochemical and electrophysiological evidence indicates that one or more GTP-binding proteins mediate many olfactory responses by coupling stimulus
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Small GTP-binding proteins as compartmental markers

Seminars in Cell Biology, 1992
Each intracellular compartment involved in the biosynthetic/secretory pathway of eukaryotic cells bears at its surface at least one small GTP-binding protein. Most of them belong to a distinct branch of the p21ras superfamily, the Sec4/Ypt1/rab family. Other proteins are members of the ARF family.
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Small GTP binding proteins and bacterial virulence

Microbes and Infection, 2000
Many bacterial toxins and bacterial enzymes modify small GTPases. Toxins exhibit different enzymatic activities on either the switch 1 or switch 2 domains of these small GTPases leading to inactivation or activation of such intracellular timer molecules.
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GTP Binding Proteins in Platelets

1999
Cells are constantly engulfed in an environment of electrical and chemical stimuli. Specific receptors enable cells to differentiate among the stimuli and relay a specific message that leads to a defined cellular response. The process that translates the stimulus-receptor interaction into an intracellular chemical message is termed signal transduction.
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GTP Binding Proteins in Postmortem Human Brain

Psychiatry and Clinical Neurosciences, 1993
E, Hashimoto, H, Ozawa, T, Saito, S, Hatta, P, Riederer, N, Takahata   +5 more
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Small GTP-binding Proteins

2008
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